382-34-3

Basic information

• Product Name: 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER
• Synonyms: 1,1,1,2,3,3-Hexafluoro-4-oxapentane;1,1,2,3,3,3-Hexafluoro-1-methoxypropane;HFE-356mec;Methyl1,1,2,3,3,3-Pentafluoropropylether;DAIKIN T-8301;1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER;1,1,1,2,3,3-HEXAFLUOROPROPYL METHYL ETHER;Methyl 1,1,2,3,3,3-hexafluoropropyl ether
• CAS NO: 382-34-3
• Molecular Formula: C₄H₄F₆O
• Molecular Weight: 182.06
• Mol File: 382-34-3.mol

Chemical Properties

• Boiling Point: 53 °C
• Appearance: /
• Density: 1.419
• Vapor Pressure: 909mmHg at 25°C
• Refractive Index: 1.283
• CAS DataBase Reference: 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER(382-34-3)
• EPA Substance Registry System: 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER(382-34-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 3271 3/PG II
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 382-34-3(Hazardous Substances Data)

Usage

Uses

Used in Electronics Manufacturing:
1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER is used as a cleaning and degreasing agent in electronics manufacturing for its ability to effectively remove contaminants and residues without the risk of combustion.
Used in Chemical Reactions and Extraction Processes:
In the chemical industry, 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER serves as a solvent for specialized reactions and extraction processes, providing a high level of purity and a low toxicity profile that enhances the safety and efficiency of these operations.
Used in Consumer Products as an Aerosol Propellant:
1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER is also utilized as an aerosol propellant in certain consumer products, offering a safer and more environmentally friendly option compared to traditional propellants.
Despite its numerous applications, it is imperative to handle and store 1,1,2,3,3,3-HEXAFLUOROPROPYL METHYL ETHER with care due to its potential health and environmental impacts.

InChI:InChI=1/C4H4F6O/c1-11-4(9,10)2(5)3(6,7)8/h2H,1H3

Upstream product

• 67-56-1 methanol 
• 116-15-4 perfluoropropylene 
• 124-41-4 sodium methylate 

Downstream Products

• 382-93-4 methyl 2,3,3,3-tetrafluoropropanoate 
• 593-53-3 Methyl fluoride 
• 6065-84-5 2,3,3,3-tetrafluoropropionylfluoride 

Relevant articles and documents

Method for removing unsaturated impurities in 1, 1, 2, 3, 3 and 3 - hexafluoropropyl hydrofluoroether crude product

The invention provides a method of removing 1. [] The hydrofluoroether impurities, pentafluoropropylene hydrofluoroether, and, 1 1 pentafluoropropylene 2 hydrofluoroether 3 impurities 3 can 3 - be well separated to provide, hexafluoropropyl hydrofluoroether product 1 having a 1 2 purity of 3 3 - at least. 1 2 1, 2, 3, 3, 3 - 3 1 1 3 3 - 99% 3 3 - 2 3The method does not use dangerous chemical, greatly improves the operation safety, does not generate waste harmful to the environment, and can be regenerated and reused by the adsorbent silica gel column. Cost is reduced, and resources are saved.

Hydrofluoroether continuous synthetic method

The invention discloses a hydrofluoroether continuous synthetic method which is characterized by comprising the following steps of mixing alcohol, a solvent and a composite catalyst, heating a mixtureto 50 DEG C, then introducing the heated mixture and fluorine-containing olefin into a tubular reactor together for reaction, and separating a reaction liquid to obtain a hydrofluoroether product, wherein the molar ratio of the alcohol, the solvent, the composite catalyst and the fluorine-containing olefin is 1 to (1-5) to (0.1-0.25) to (1-1.5), the reaction temperature is 50-150 DEG C, and the reaction time is 5-25s. By adopting the hydrofluoroether continuous synthetic method provided by the invention, a synthetic process is improved so as to be the hydrofluoroether continuous synthetic method which is simple in synthetic process, large in operation flexibility and low in cost and is environmentally friendly.

Fluorine gas for life science syntheses: Green metrics to assess selective direct fluorination for the synthesis of 2-fluoromalonate esters

Optimisation and real time reaction monitoring of the synthesis of 2-fluoromalonate esters by direct fluorination using fluorine gas is reported. An assessment of green metrics including atom economy and process mass intensity factors, demonstrates that the one-step selective direct fluorination process compares very favourably with established multistep processes for the synthesis of fluoromalonates.

Palladium(0)-catalyzed hydroalkoxylation of hexafluoropropene: Synthesis of hydrofluoroethers under neutral conditions

No vinyl ether by-products are formed in the palladium(0)-complex catalyzed hydroalkoxylation of hexafluoropropene (see scheme). Saturated hydrofluoro-ethers are selectively synthesized with alcohols or phenols under neutral conditions in the presence of

Synthesis and use of partially fluorinated dialkyl ethers derived from hexafluoropropylene

A procedure was developed for preparing partially fluorinated dialkyl ethers by the reaction of hexafluoropropylene with aliphatic and polyfluorinated alcohols in the presence of KOH. On treatment with concentrated sulfuric acid, these ethers form alkyl esters of acids, and on treatment with KOH, alkenyl ethers.

FACILE SYNTHESIS OF DIALKYL FLUOROMALONATES AND THEIR DERIVATIVES

Dimethyl and diethyl fluoromalonates were prepared by the stepwise basic alcoholysis of hexafluoropropene in a total yield of 50 - 55 percent.These dialkyl fluoromalonates were alkylated with alkyl halides, and the resulting dialkyl α-fluoroalkylmalonates were cyclized with urea affording 5-fluorobarbituric acid derivatives.