1,1,2,3,3,3-Hexafluoropropyl methyl ether

Base Information

• Chemical Name: 1,1,2,3,3,3-Hexafluoropropyl methyl ether
• CAS No.: 382-34-3
• Molecular Formula: C4H4F6O
• Molecular Weight: 182.066
• Hs Code.: 2909199090
• UNII: YO51Z7KN9E
• DSSTox Substance ID: DTXSID80959148
• Nikkaji Number: J82.345G
• Mol file: 382-34-3.mol

Synonyms:1,1,2,3,3,3-hexafluoropropyl methyl ether;HFPME

Chemical Property of 1,1,2,3,3,3-Hexafluoropropyl methyl ether

Chemical Property:

• Appearance/Colour: liquid
• Vapor Pressure: 909mmHg at 25°C
• Refractive Index: 1.283
• Boiling Point: 20 °C at 760 mmHg
• Flash Point: <21oC
• PSA: 9.23000
• Density: 1.357 g/cm³
• LogP: 2.12600
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 182.01663372
• Heavy Atom Count: 11
• Complexity: 129

Purity/Quality:

97% ^*data from raw suppliers

1,1,2,3,3,3-Hexafluoropropyl Methyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(C(C(F)(F)F)F)(F)F

Technology Process of 1,1,2,3,3,3-Hexafluoropropyl methyl ether

There total 3 articles about 1,1,2,3,3,3-Hexafluoropropyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) → 1,1,1,2,3,3-hexafluoro-3-methoxypropane (382-34-3)

Guidance literature:

With sodium; for 1.5h;

DOI:10.1023/B:RJAC.0000024585.14553.5f

Reference yield:

perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) + sodium methylate (124-41-4) → 1,1,1,2,3,3-hexafluoro-3-methoxypropane (382-34-3)

Guidance literature:

In methanol; Yield given; 1.) 3 h, 2.) room temperature;

DOI:10.1246/cl.1981.107

Reference yield:

→ 1,1,1,2,3,3-hexafluoro-3-methoxypropane (382-34-3)

Guidance literature:

1.1.2.3.3.3-Hexafluor-propen, H2O2, KOH, wss. Me.-Lsg, -40 ca -30 grad;

upstream raw materials:

methanol

perfluoropropylene

sodium methylate

Downstream raw materials:

methyl 2,3,3,3-tetrafluoropropanoate

Methyl fluoride

2,3,3,3-tetrafluoropropionylfluoride