4093-88-3

Basic information

• Product Name: METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE
• Synonyms: METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE;N-METHYL-3-NITRO-2-PYRIDINAMINE;2-(Methylamino)-3-nitropyridine;N-METHYL-3-NITROPYRIDIN-2-AMINE;2-Pyridinamine, N-methyl-3-nitro-;methyl-(3-nitro-2-pyridyl)amine
• CAS NO: 4093-88-3
• Molecular Formula: C₆H₇N₃O₂
• Molecular Weight: 153.13868
• Mol File: 4093-88-3.mol

Chemical Properties

• Melting Point: 67-69
• Boiling Point: 287.3 °C at 760 mmHg
• Flash Point: 127.6 °C
• Appearance: /
• Density: 1.343 g/cm³
• Vapor Pressure: 0.0025mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.87±0.10(Predicted)
• CAS DataBase Reference: METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE(4093-88-3)
• EPA Substance Registry System: METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE(4093-88-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 4093-88-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE serves as a precursor in the production of agrochemicals, aiding in the creation of compounds that protect crops and enhance agricultural productivity.
Used in Fine Chemicals Production:
METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE is utilized as a building block in the manufacture of fine chemicals, which are essential in various industries such as cosmetics, fragrances, and flavorings.
Used in Specialty Materials Industry:
METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE is also employed in the production of specialty materials, which have unique properties and are used in specific applications across different industries, including electronics and advanced materials.
Due to its potential health and environmental hazards, METHYL-(3-NITRO-PYRIDIN-2-YL)-AMINE requires careful handling and storage to ensure safety in its applications.

InChI:InChI=1/C6H7N3O2/c1-7-6-5(9(10)11)3-2-4-8-6/h2-4H,1H3,(H,7,8)

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 152339-61-2 N-methyl-N-(2-pyridyl)-nitramine 
• 7664-93-9 sulfuric acid 
• 90819-94-6 1,2-dihydro-1-methyl-2-nitriminopyridine 
• 74-89-5 methylamine 
• 4214-75-9 2-amino-3-nitropyridine 
• 74-88-4 methyl iodide 
• 123-39-7 N-Methylformamide 
• 79-16-3 N-methyl-acetamide 
• 1480-87-1 2-fluoro-3-nitropyridine 

Downstream Products

• 30458-69-6 3-methyl-3H-imidazo[4,5-b]pyridin-2-amine 
• 107351-86-0 N²-methyl-5-phenylpyridine-2,3-diamine 
• 1401817-89-7 2-(4-methoxyphenyl)-3-methyl-3H-imidazo[4,5-b]pyridine 
• 6688-61-5 3-methyl-3H-imidazo[4,5-b]pyridine 
• 5028-20-6 3-amino-2-methylaminopyridine 
• 152684-20-3 N-methyl-3-nitro-5-phenylpyridin-2-amine 
• 80708-25-4 4-methyl-1,4-dihydropyrido[2,3-b]piperazine-2,3-dione 
• 74-89-5 methylamine 
• 19404-40-1 2-Methylamino-3,5-dinitropyridin 
• 103698-07-3 methyl-nitro-(3-nitro-[2]pyridyl)-amine 
• 6332-56-5 2-hydroxy-3-nitropyridine 

Relevant articles and documents

Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes

CuH-catalyzed intramolecular cyclization and intermolecular allylation of benzimidazoles with allenes have been described. The reaction proceeded smoothly with the catalytic system of Cu(OAc)2/Xantphos and catalytic amount of (MeO)2MeSiH. This protocol features mild reaction conditions and a good tolerance of substrates bearing electron-withdrawing, electron-donating, or electron-neutral groups. A new catalytic mechanism was proposed for this copper hydride catalytic system.

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The synthesis and characterization of cyclometalated C^C* platinum(II) complexes with unique photophysical properties, aggregation induced enhancement of the quantum yields with a simultaneous decrease of phosphorescence lifetimes, is reported. Additional

Imidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles

The development of a reagent for the efficient synthesis of five- and six-membered azoles at room temperature is proposed. A variety of substituted 2-aminobenzimidazoles are synthesized in good to excellent yields. The ability to incorporate various protecting groups makes the imidoyl dichloride reagent amenable to a large number of syntheses. The reagent is applied to the total synthesis of the 2-aminobenzimidazole containing carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), from 2-chloro-3-nitropyridine in >60% yield in 6 steps.

PYRIDYL CARBENE PHOSPHORESCENT EMITTERS

Organometallic compounds comprising an imidazole carbene ligand having a N-containing ring fused to the imidazole ring are provided. In particular, the N-containing ring fused to the imidazole ring may contain one nitrogen atom or more than one nitrogen a

PYRIDYL CARBENE PHOSPHORESCENT EMITTERS

Organometallic compounds comprising an imidazole carbene ligand having a N- containing ring fused to the imidazole ring are provided. In particular, the N-containing ring fused to the imidazole ring may contain one nitrogen atom or more than one nitrogen

A simple synthesis of aminopyridines: Use of amides as amine source

A transition metal/microwave irradiation (or base) free synthesis of aminopyridines has been accomplished via C-N bond forming reaction between chloropyridine and a variety of simple amides under refuxing conditions.

Efficient and selective method for the synthesis of dihydrodipyridopyrazines based on the pd-catalysed animation of halopyridines

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