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2-Methyl-2-phenylbutanoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 51018-80-5 Structure
  • Basic information

    1. Product Name: 2-Methyl-2-phenylbutanoic acid
    2. Synonyms: Benzeneacetic acid, α-ethyl-α-methyl-;Benzeneacetic acid, α-ethyl-α-methyl-, (±)-
    3. CAS NO:51018-80-5
    4. Molecular Formula: C11H14O2
    5. Molecular Weight: 178.22766
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 51018-80-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Methyl-2-phenylbutanoic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Methyl-2-phenylbutanoic acid(51018-80-5)
    11. EPA Substance Registry System: 2-Methyl-2-phenylbutanoic acid(51018-80-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 51018-80-5(Hazardous Substances Data)

51018-80-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51018-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,0,1 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51018-80:
(7*5)+(6*1)+(5*0)+(4*1)+(3*8)+(2*8)+(1*0)=85
85 % 10 = 5
So 51018-80-5 is a valid CAS Registry Number.

51018-80-5Relevant articles and documents

Nickel-catalysed direct alkylation of thiophenes via double C(sp3)-H/C(sp2)-H bond cleavage: The importance of KH2PO4

Wang, Xie,Xie, Peipei,Qiu, Renhua,Zhu, Longzhi,Liu, Ting,Li, You,Iwasaki, Takanori,Au, Chak-Tong,Xu, Xinhua,Xia, Yuanzhi,Yin, Shuang-Feng,Kambe, Nobuaki

, p. 8316 - 8319 (2017/07/26)

A Ni-catalyzed oxidative C-H/C-H cross-dehydrogenative coupling (CDC) reaction was developed for constructing various highly functionalized alkyl (aryl)-substituted thiophenes. This method employs thiophenes and aliphatic (aromatic) amides that contain an 8-aminoquinoline as a removable directing group in the presence of a silver oxidant. The approach enables the facile one-step synthesis of substituted thiophenes with high functional group compatibility via double C-H bond cleavage without affecting C-Br and C-I bonds. DFT calculations verify the importance of KH2PO4 as an additive for promoting C-H bond cleavage and support the involvement of a Ni(iii) species in the reaction.

Nickel-catalyzed site-selective alkylation of unactivated C(sp 3)-H bonds

Wu, Xuesong,Zhao, Yan,Ge, Haibo

supporting information, p. 1789 - 1792 (2014/03/21)

The direct alkylation of unactivated sp3 C-H bonds of aliphatic amides was achieved via nickel catalysis with the assist of a bidentate directing group. The reaction favors the C-H bonds of methyl groups over the methylene C-H bonds and tolerates various functional groups. Moreover, this reaction shows a predominant preference for sp3 C-H bonds of methyl groups via a five-membered ring intermediate over the sp2 C-H bonds of arenes in the cyclometalation step.

Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: Synthesis of chiral benzofuranones

Cheng, Xiu-Fen,Li, Yan,Su, Yi-Ming,Yin, Feng,Wang, Jian-Yong,Sheng, Jie,Vora, Harit U.,Wang, Xi-Sheng,Yu, Jin-Quan

supporting information, p. 1236 - 1239 (2013/03/14)

Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.

UREA COMPOUNDS AS GAMMA SECRETASE MODULATORS

-

, (2010/01/29)

The present invention provides compounds Formula (I) that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Synthesis and photochemistry of (2S,4R)- and (2R,4R)-1,2,3,4-tetrahydro-4-ethyl-1,1,4-trimethyl-3Z-ethylidene-2-naphthalenols

Miesen, F. W. A. M.,Dongen, J. L. J. van,Meijer, E. W.

, p. 307 - 317 (2007/10/02)

The synthesis and photochemistry of optically pure (2S,4R)- and (2R,4R)-1,2,3,4-tetrahydro-4-ethyl-1,1,4-trimethyl-3Z-ethyliden-2-naphthalenols 10a and 11a are described.Naphthalenols 10a and 11a were prepared in seven steps from 2-phenylbutanenitrile.Syn

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