5410-97-9

Basic information

• Product Name: 3-Nitrodibenzofuran
• Synonyms: 3-NITRODIBENZOFURAN;3-Nitrodibenzo[b,d]furan;3-nitro-dibenzofura;Dibenzofuran, 3-nitro-;11-nitro-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaene;NSC 10862
• CAS NO: 5410-97-9
• Molecular Formula: C₁₂H₇NO₃
• Molecular Weight: 213.19
• Product Categories: Fluorobenzene;Furans
• Mol File: 5410-97-9.mol

Chemical Properties

• Melting Point: 181.5°C
• Boiling Point: 353.17°C (rough estimate)
• Flash Point: 183.4 °C
• Appearance: /
• Density: 1.2911 (rough estimate)
• Vapor Pressure: 1.26E-05mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-Nitrodibenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitrodibenzofuran(5410-97-9)
• EPA Substance Registry System: 3-Nitrodibenzofuran(5410-97-9)

Safety Data

• Hazardous Substances Data: 5410-97-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Nitrodibenzofuran is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Anti-Cancer Research:
3-Nitrodibenzofuran is used as a subject of research in anti-cancer treatments. Its mutagenic and cytotoxic properties have been studied for their potential to target and eliminate cancer cells. However, due to its potential toxicity, further research is necessary to explore its safe and effective use in cancer therapy.
Used in Environmental and Health Risk Assessment:
Given its potential toxicity and environmental concerns, 3-Nitrodibenzofuran is used in studies to assess and manage the risks associated with its production, handling, and disposal. This helps in developing guidelines and protocols for safe usage and disposal to minimize its impact on human health and the environment.

InChI:InChI=1/C12H7NO3/c14-13(15)8-5-6-10-9-3-1-2-4-11(9)16-12(10)7-8/h1-7H

Upstream product

• 132-64-9 dibenzofuran 
• 99586-25-1 3-nitro-dibenzofuran-2-carboxylic acid 
• 854395-60-1 7-nitro-dibenzofuran-4-carboxylic acid 
• 5422-92-4 1-amino-2-phenoxy-4-nitrobenzene 
• 104-82-5 4-Methylbenzyl chloride 
• 65103-30-2 4-nitrophenyl 2-(allyloxy)benzoate 
• 620-55-3 1-nitro-3-phenoxybenzene 
• 56-23-5 tetrachloromethane 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 100725-65-3 3-nitro-2-ethyldibenzo[b,d]furan 
• 66283-60-1 dibenzofuran carboxylic acid chloride 
• 2786-05-2 dibenzofuran-4-carboxylic acid 
• 4106-66-5 3-aminodibenzofuran 

Downstream Products

• 173846-17-8 1-(7-nitro-dibenzofuran-2-yl)-ethanone 
• 25074-67-3 3-chlorodibenzofuran 
• 51596-37-3 2-chloro-7-nitro-dibenzofuran 
• 5408-55-9 2,7-dinitrodibenzofuran 
• 873974-45-9 2,3,8-trinitro-dibenzofuran 
• 42138-14-7 dibenzofuran-3-sulphonyl chloride 
• 98045-13-7 7-nitrodibenzo[b,d]furan-2-sulfonyl chloride 
• 5896-29-7 3-iododibenzo[b,d]furan 

Relevant articles and documents

3-Nitrodibenzofuran and 3-Iododibenzofuran

The structures of 3-nitrodibenzofuran, C12H7NO3, and 3-iododibenzofuran, C12H7IO, have been determined.Both molecules are nearly planar and pack in herringbone patterns composed of symmetry related head-to-tail pairs with parallel ? systems.

Triarylated amine derivative and organic electroluminescence device with same

The invention discloses a triarylated amine derivative and an organic electroluminescence device with the same, and relates to the technical field of organic photoelectric materials. The triarylated amine derivative has a large conjugated system, thereby having high hole mobility and presenting good hole transmissibility; in addition, the triarylated amine derivative has high thermal stability anddissolubility and is beneficial for material film forming. The organic electroluminescence device comprises a cathode, an anode and one or more organic matter layers. The organic matter layers are located between the cathode and the anode. At least one of the organic matter layers contains the triarylated amine derivative. The organic electroluminescence device has low driving voltages, high light-emitting efficiency, light-emitting luminance and long service life.

NOVEL TRIAZINE COMPOUND, AND ORGANIC ELECTRONIC ELEMENT AND PLANT-GROWING LIGHTING THAT USE THE SAME

PROBLEM TO BE SOLVED: To provide a triazine compound which has a high triplet energy level and excellent heat resistance, and can be used as an organic electronic element material realizing an element with high efficiency, low voltage and a long life. SOLUTION: In the triazine compound, as represented by the general formula [1] in the figure, a triazine backbone moiety is linked to a dibenzofuran or dibenzothiophene backbone moiety via a biphenyl backbone moiety, where X is an oxygen atom or sulfur atom. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPO&INPIT

Visible-Light-Promoted Synthesis of Dibenzofuran Derivatives

Dibenzofurans are naturally occurring molecules that have received considerable attention for a variety of practical applications, such as in pharmaceuticals and electronic materials. Herein, an efficient and eco-friendly method for the synthesis of dibenzofuran derivatives via intramolecular C-O bond formation, which involves the in situ production of a diazonium salt, is described. The transformation requires a diazotizing agent and is promoted by the use of an organic photosensitizer under visible-light irradiation.

With Wnt signal path to inhibit the active heterocyclic compounds (by machine translation)

The invention relates to a signal path with Wnt inhibiting activity of a heterocyclic compound, including the compound and its pharmaceutically acceptable salt, various isotope, various isomers or various crystal structure, having the general formula I of the structure shown in: the invention relates to a compound and its joint application composition can effectively inhibit the Wnt signal path, can be used for the treatment or prevention of a disorder associated with a Wnt signal path. (by machine translation)

A thermally stable anthracene derivative for application in organic thin film transistors

A novel multifunctional anthracene derivative 2,6-bis(dibenzo[b,d]furan-3-yl)anthracene) (BDBFAnt), by coupling anthracene moiety with dibenzo[b,d]furan units attached to its peripheral position, has been designed and synthesized for application in OTFT devices. Introduction of dibenzo[b,d]furan units in OTFTs is the first example and is highly innovative due to their suitable carrier transport ability, excellent thermal stability, fine film-forming property, rigid planarity and outstanding fluorescence. The fabricated OTFTs demonstrate a decent hole mobility (3.0?cm2/V s) and favorable green solid fluorescence with excellent thermal stability (up to 220?°C), which expound on the great potential of our material in organic electronics.

Microwave-Promoted Pd-Catalyzed Synthesis of Dibenzofurans from Ortho-Arylphenols

ortho-Aryl phenols, synthesized via protecting group free Suzuki–Miyaura coupling of ortho-halophenols and arene boronic acids, undergo a cyclization to dibenzofurans via oxidative C–H activation. The reaction proceeds under microwave irradiation in short reaction times using catalytic amounts of Pd(OAc)2 without additional ligands.

Phosphorescent iridium complex containing 3-phenyl pyridazine structure, and applications thereof

The invention discloses a phosphorescent iridium complex containing a 3-phenyl pyridazine structure, and applications thereof. Metal iridium is taken as the inner core of the phosphorescent iridium complex, and the phosphorescent iridium complex is taken

Phosphorescent iridium complex serving as OLED (organic light emitting diode) doping material

The invention discloses a phosphorescent iridium complex serving as an OLED (organic light emitting diode) doping material. According to the iridium complex, metal iridium is taken as a structural inner core and applied to an OLED device and can emit phos

Double functionalization of 2-amino-2′-hydroxy-1,1′-biaryls: Synthesis of 4-nitro-dibenzofurans and benzofuro-indoles

Several substituted 2′-amino-biphenyl-2-ols were synthesized. The mild and TM-free double functionalization: nitration and cycloetherification of 2′-amino-biphenyl-2-ols have been achieved for the synthesis of functionalized 4-nitro-dibenzofurans utilizing NaNO2 in TFA and water. Interestingly, nitration of phenol ring was observed along with the dibenzofuran ring formation in the one-pot synthesis. The position of the nitro group in several dibenzofurans is also established by X-ray crystal structure studies. Further functionalization of the obtained 4-nitro-dibenzofurans has been carried into 3-nitro-terphenyl-2-ol, novel benzofuro-indoles, and amino-dibenzofurans. The mechanistic understanding on double functionalization of 2′-amino-biphenyl-2-ols suggests that reaction proceeds by a combination of nitration of the phenol ring followed by Sandmeyer reaction for dibenzofuran ring formation.