Welcome to LookChem.com Sign In|Join Free

CAS

  • or
H-ALA-NHME HCL is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

61275-22-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 61275-22-7 Structure
  • Basic information

    1. Product Name: H-ALA-NHME HCL
    2. Synonyms: H-ALA-NHME HCL;L-ALANINE METHYLAMIDE HYDROCHLORIDE;L-ALANINE N-METHYLAMIDE HYDROCHLORIDE;ALANINE-NHME HCL;N~1~-methyl-L-alaninamide hydrochloride;propanamide, 2-amino-N-methyl-, (2S)-;H-Ala-NHMe;(S)-2-AMino-N-MethylpropanaMide hydrochloride
    3. CAS NO:61275-22-7
    4. Molecular Formula: C4H10N2O*ClH
    5. Molecular Weight: 138.6
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 61275-22-7.mol
  • Chemical Properties

    1. Melting Point: 218-220 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
    2. Boiling Point: 257°C at 760 mmHg
    3. Flash Point: 109.2°C
    4. Appearance: /
    5. Density: 0.976g/cm3
    6. Vapor Pressure: 0.0149mmHg at 25°C
    7. Refractive Index: 1.442
    8. Storage Temp.: Store at 0-5°C
    9. Solubility: N/A
    10. CAS DataBase Reference: H-ALA-NHME HCL(CAS DataBase Reference)
    11. NIST Chemistry Reference: H-ALA-NHME HCL(61275-22-7)
    12. EPA Substance Registry System: H-ALA-NHME HCL(61275-22-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 61275-22-7(Hazardous Substances Data)

61275-22-7 Usage

Chemical Properties

White powder or solid

Uses

H-Ala-NHMe HCl

Check Digit Verification of cas no

The CAS Registry Mumber 61275-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,7 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61275-22:
(7*6)+(6*1)+(5*2)+(4*7)+(3*5)+(2*2)+(1*2)=107
107 % 10 = 7
So 61275-22-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H10N2O/c1-3(5)4(7)6-2/h3H,5H2,1-2H3,(H,6,7)/t3-/m0/s1

61275-22-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-2-Amino-N-methylpropanamide hydrochloride

1.2 Other means of identification

Product number -
Other names (2S)-2-amino-N-methylpropanamide,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61275-22-7 SDS

61275-22-7Relevant articles and documents

INHIBITORS OF RAF KINASES

-

Paragraph 00852; 00855-00856, (2021/04/30)

Provided herein are inhibitors of receptor tyrosine kinase effector, RAF, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

Straightforward Synthesis of Fluorinated Enals via Photocatalytic α-Perfluoroalkenylation of Aldehydes

Wulkesch, Christian,Czekelius, Constantin

, p. 7425 - 7438 (2021/06/21)

(Per)fluorinated substances represent an important compound class with regard to drug design and material chemistry. We found a mild, operationally simple, and inexpensive photocatalytic perfluoroalkenylation reaction giving tetrasubstituted, highly electron-deficient enals straight from aldehydes. This one-step reaction tolerates various functional groups and can be applied to a wide range of substrates giving the products in yields of 52-84%.

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates

Ponath, Sebastian,Menger, Martina,Grothues, Lydia,Weber, Manuela,Lentz, Dieter,Strohmann, Carsten,Christmann, Mathias

supporting information, p. 11683 - 11687 (2018/09/10)

Herein we report the isolation and characterization of aminal intermediates in the organocatalytic α-chlorination of aldehydes. These species are stable covalent ternary adducts of the substrate, the catalyst and the chlorinating reagent. NMR-assisted kinetic studies and isotopic labeling experiments with the isolated intermediate did not support its involvement in downstream stereoselective processes as proposed by Blackmond. By tuning the reactivity of the chlorinating reagent, we were able to suppress the accumulation of rate-limiting off-cycle intermediates. As a result, an efficient and highly enantioselective catalytic system with a broad functional group tolerance was developed.

Organocatalytic regiospecific synthesis of 1H-indene-2-carbaldehyde derivatives: suppression of cycloolefin isomerisation by employing sterically demanding catalysts

Mao, Hui,Kim, Dong Wan,Shin, Hun Yi,Song, Choong Eui,Yang, Jung Woon

supporting information, p. 1355 - 1362 (2017/02/15)

The regiospecific synthesis of 1H-indene-2-carbaldehyde derivatives was achieved through transition-metal-free, reductive cyclisation of ortho-formyl trans-cinnamaldehydes with Hantzsch ester in the presence of an aminocatalyst. In particular, cycloolefin isomerisation of the resulting products could be inhibited efficiently by the introduction of a sterically demanding stereo-defined aminocatalyst.

Preparation of the MacMillan imidazolidinones

Samulis, Leopold,Tomkinson, Nicholas C.O.

experimental part, p. 4263 - 4267 (2011/06/26)

A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb(OTf)3 (1 mol %) provides convenient access to the corresponding imidazolidinones.

Highly efficient stereoconservative amidation and deamidation of α-amino acids

Shendage, Deepak M.,Froehlich, Roland,Haufe, Guenter

, p. 3675 - 3678 (2007/10/03)

(Chemical Equation Presented) An overall stereoconservative protection and deprotection method of amino and carboxyl groups is presented. N-Phthaloyl N-alkyl secondary amides of α-amino acids can be generated from corresponding N-phthaloyl amino acids by coupling reaction of N-alkylamines using mixed anhydride method. These secondary amides can be transformed by thermal rearrangement of intermediate nitrosoamides to O-alkyl esters with retention of configuration and excellent yields.

Structural and thermodynamic characterization of temperature-dependent changes in the folding pattern of a synthetic triamide

Dado, Gregory P.,Gellman, Samuel H.

, p. 4228 - 4245 (2007/10/02)

Variable-temperature 1H NMR and IR studies of triamide 1 and related compounds indicate that 1 undergoes dramatic temperature-dependent conformational changes in relatively nonpolar solvents (methylene chloride and chloroform). The folding pattern favored at low temperatures in these chlorocarbons (1c) contains a single C=O?H-N hydrogen bond in a nine-membered ring, while a folding pattern containing only a six-membered-ring C=O?N-H interaction (1a) is favored at higher temperatures. Dimethyl sulfoxide, a very strong hydrogen-bond-accepting solvent, disrupts all internal hydrogen bonding in 1. Acetonitrile appears to disrupt the six-membered-ring hydrogen bond selectively and to promote nine-membered-ring interaction at room temperature, relative to chlorocarbon solvents. By treating the behavior of 1 as a two-state system, in which folding pattern 1c is considered to be the "native state" and all other folding patterns comprise the "denatured state", we have been able to carry out van't Hoff analyses of the temperature-dependent conformational changes. In methylene chloride, the native state is enthalpically preferred by 1.9-2.5 kcal/mol but entropically disfavored by 7.4-9.1 eu. Similar values are obtained in chloroform. This thermodynamic characterization demonstrates that, even in a relatively nonpolar environment, the relative enthalpic stabilities of alternative folding patterns cannot be predicted simply by maximizing the pairing of hydrogen-bond donors and acceptors.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 61275-22-7