621-12-5

Basic information

• Product Name: 1,4-DIPHENYLSEMICARBAZIDE
• Synonyms: N,N'-Diphenyl semicarbazide;Semicarbazide, 1,4-diphenyl-;1,4-DIPHENYLSEMICARBAZIDE;Diphenylsemicarbazide;1-(anilino)-3-phenylurea;1-(anilino)-3-phenyl-urea;1-phenyl-3-(phenylamino)urea;Hydrazinecarboxamide, N,2-diphenyl-
• CAS NO: 621-12-5
• Molecular Formula: C₁₃H₁₃N₃O
• Molecular Weight: 227.26
• Mol File: 621-12-5.mol

Chemical Properties

• Melting Point: 181 °C
• Appearance: Colorless needle-like crystal
• Density: 1.271 g/cm³
• Refractive Index: 1.694
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1,4-DIPHENYLSEMICARBAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIPHENYLSEMICARBAZIDE(621-12-5)
• EPA Substance Registry System: 1,4-DIPHENYLSEMICARBAZIDE(621-12-5)

Safety Data

• Hazardous Substances Data: 621-12-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Analysis:
1,4-Diphenylsemicarbazide is used as a reagent for the determination of carbonyl compounds and other organic substances in pharmaceutical analysis. It aids in identifying and quantifying specific chemicals in drug formulations, ensuring their purity and quality.
Used in Environmental Analysis:
1,4-Diphenylsemicarbazide is employed as a reagent in environmental analysis for testing water and food products. It helps in detecting the presence of specific chemicals, contributing to the assessment of environmental contamination and ensuring the safety of consumable products.
Used in Analytical Chemistry:
1,4-Diphenylsemicarbazide is used as a reagent in various analytical chemistry applications, particularly for the identification and quantification of organic substances. Its hydrazine-like structure makes it a valuable tool in the analysis of complex chemical mixtures and compounds.

InChI:InChI=1/C13H13N3O/c17-13(14-11-7-3-1-4-8-11)16-15-12-9-5-2-6-10-12/h1-10,15H,(H2,14,16,17)

Upstream product

• 62-53-3 aniline 
• 6233-02-9 ethyl phenylhydrazocarboxylate 
• 64-17-5 ethanol 
• 603-54-3 N,N-diphenylurea 
• 100-63-0 phenylhydrazine 
• 77331-32-9 5-Isobutyl-3-methylsulfanyl-1,4-diphenyl-4H-[1,2,4]triazol-1-ium; iodide 
• 54211-56-2 3-methyl-1,4-diphenyl isothiosemicarbazide 
• 86298-24-0 N-phenyl-1H-benzo[d][1,2,3]triazole-1-carboxamide 
• 65-85-0 benzoic acid 
• 77331-28-3 3-methylthio-1,4-diphenyl-1,2,4-triazolium chloride 
• 77331-36-3 3-Methylsulfanyl-5-((Z)-octadec-9-enyl)-1,4-diphenyl-4H-[1,2,4]triazol-1-ium; iodide 
• 103-71-9 phenyl isocyanate 
• 71-43-2 benzene 
• 60-29-7 diethyl ether 

Downstream Products

• 854819-80-0 2-phenyl-3-phenylcarbamoyl-carbazic acid ethyl ester 
• 60027-25-0 1-acetyl-1,4-diphenyl semicarbazide 
• 60027-26-1 1-formyl-1,4-diphenyl semicarbazide 
• 34874-03-8 1,4-Diphenyl-1,2,4-triazolidin-3,5-dion 
• 101117-88-8 3,5-dioxo-2-phenyl-pyrazolidine-1-carboxylic acid anilide 
• 110375-62-7 4-butyl-3,5-dioxo-2-phenyl-pyrazolidine-1-carboxylic acid anilide 
• 52353-62-5 4-anilino-1-phenyl-1,2,4-triazolidine-3,5-dione 
• 70002-96-9 N-phenyl-2-phenyldiazenecarboxamide 
• 95-71-6 2-methylbenzene-1,4-diol 
• 1133143-35-7 C₂₃H₃₃N₃O₄ 
• 1133143-33-5 C₂₁H₂₉N₃O₄ 
• 1133143-27-7 C₁₉H₂₅N₃O₄ 
• 1133143-25-5 dimethyl 5-(tert-butylamino)-1-phenyl-1H-pyrazole-3,4-dicarboxylate 
• 1133143-31-3 C₂₁H₂₇N₃O₄ 

Relevant articles and documents

One-pot preparation of carbamoyl benzotriazoles and their applications in the preparation of ureas, hydrazinecarboxamides and carbamic esters

Carbamoyl benzotriazoles were conveniently synthesized in one-pot from carboxylic acids, diphenyl phosphorazidate (DPPA) and 1H-benzotriazole (BtH). The reactivity and applications of carbamoyl benzotriazoles were also explored. Carbamoyl benzotriazoles react smoothly with amino acids, hydrazines and alcohols, thus providing facile access to the corresponding ureas, hydrazinecarboxamides and carbamic esters, respectively, in good to excellent yields.

Synthesis and characterization of new diazenecarboxamide ligands using a selective adduct formation with B(C6F5)3

The synthesis and structure of new N-(2,6-diisopropylphenyl)-2-phenyldiazenecarboxamide (L2) and N-(2,6-diisopropylphenyl)-2 (perfluorophenyl) diazenecarboxamide (L3) ligands are described. The subsequent reactions of ligands L1

Synthesis of unsymmetrical ureas and S-thiocarbamates under catalyst-free conditions in a [BMIM]BF4 ionic liquid

Unsymmetrical ureas and Sthiocarbamates were prepared in good to excellent yields by direct condensation of phenylurea with amines and thiols in 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]BF4) without the addition of any additives. The [BMIM]BF4 ionic liquid is a mild medium and can be recycled and reused several times.

THE CHAIN LENGTHENING OF ALIPHATIC ALDEHYDES WITH THE AID OF "NUCLEOPHILIC CARBENE"

The addition of "nucleophilic carbene" on 1,2,4-triazole bases (2) and aldehydes is decisively influenced by the anion present. 5-(α-Hydroxyalkyl)-1,2,4-triazolium chlorides, formed in the addition reaction of 3-methylthio-1,4-diphenyl-1,2,4-triazolium chloride (1c) with aldehydes, can be easily reduced to 5-alkyl-1,2,4-triazolium iodides (5).Reduction of these with NaBH4 affords aldehydes by acidic hydrolysis or carboxylic acids by alkaline hydrolysis, the carbon chain of which has been lengthened by one CH2 group, as compared to the starting aldehyde.