930-61-0

Basic information

• Product Name: 2,4-DIMETHYL-2-IMIDAZOLINE
• Synonyms: 4,5-dihydro-2,4-dimethyl-1h-imidazol;2,4-DIMETHYL-2-IMIDAZOLINE;4,5-dihydro-2,4-dimethyl-1H-imidazole;2,5-dimethyl-4,5-dihydro-1H-imidazole;1H-IMidazole, 4,5-dihydro-2,4-diMethyl-
• CAS NO: 930-61-0
• Molecular Formula: C₅H₁₀N₂
• Molecular Weight: 98.15
• EINECS: 213-220-9
• Mol File: 930-61-0.mol

Chemical Properties

• Boiling Point: 198.6°Cat760mmHg
• Flash Point: 73.9°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.504mmHg at 25°C
• Refractive Index: 1.4806
• PKA: 11.04±0.70(Predicted)
• CAS DataBase Reference: 2,4-DIMETHYL-2-IMIDAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHYL-2-IMIDAZOLINE(930-61-0)
• EPA Substance Registry System: 2,4-DIMETHYL-2-IMIDAZOLINE(930-61-0)

Safety Data

• Statements: 36/38
• Safety Statements: 26-36
• TSCA: Yes
• Hazardous Substances Data: 930-61-0(Hazardous Substances Data)

Usage

Uses

Used in Veterinary Medicine:
2,4-DIMETHYL-2-IMIDAZOLINE is used as a sedative and analgesic for inducing calmness and pain relief in animals, particularly in species such as horses, cattle, and deer. Its application is primarily due to its effectiveness in causing sedation, muscle relaxation, and anesthetic effects by acting on central nervous system receptors.
Used in Combination Therapy with Ketamine:
2,4-DIMETHYL-2-IMIDAZOLINE is used in combination with ketamine as a sedative and analgesic agent to enhance the sedative and analgesic effects in animals. This combination is particularly beneficial for procedures that require a higher level of sedation and pain control.

InChI:InChI=1/C5H10N2/c1-4-3-6-5(2)7-4/h4H,3H2,1-2H3,(H,6,7)

Upstream product

• 534-26-9 lysidine 
• 78-90-0 1,2-diaminopropan 
• 35397-63-8 1-methyl-2-(methylcarbonylamino)ethylamine 
• 127-09-3 sodium acetate 
• 123-86-4 acetic acid butyl ester 

Downstream Products

• 14331-54-5 2,4-dimethylpyrimidine 
• 123-32-0 2,5-dimethyl-pyrazine 
• 54198-89-9 5-chloro-2-methylpyrimidine 
• 4472-45-1 4-chloro-2,6-dimethylpyrimidine 
• 95-89-6 2,5-dimethyl-3-chloropyrazine 
• 38557-72-1 2-chloro-3,5-dimethylpyrazine 
• 75712-74-2 4-chloro-2,5-dimethylpyrimidine 
• 4994-86-9 4-chloro-2-methylpyrimidine 
• 693-98-1 2-methylimidazole 
• 75712-73-1 5-Chloro-2,4-dimethylpyrimidine 
• 5053-43-0 2-methylpyrimidine 
• 930-62-1 2,4-Dimethylimidazole 
• 95-58-9 2-chloro-3-methylpyrazine 
• 108-50-9 2,6-dimethylpyrazine 

Relevant articles and documents

METHOD FOR PRODUCING IMIDAZOLINE COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing an imidazoline compound having high yield and small amount of impurity. SOLUTION: There is provided a method for producing an imidazoline compound (B) using a diamine monoamide compound (A) represented by the general formula (1), wherein the method includes a dehydration condensation step of the diamine monoamide compound (A) and a distillation step of the imidazoline compound (B). In the dehydration condensation step, the temperature of the dehydration condensation reaction of (A) is 100°C to 160°C in a time of 50% or more of the process time from when the conversion rate from (A) to (B) becomes 55% until when the conversion rate from (A) to (B) becomes 70%, and a the gas-phase pressure at the temperature of the dehydration condensation reaction of (A) is P1 which satisfies the conditions 1. In the distillation step, the temperature of the liquid containing (A) and (B) is 100°C to 190°C in a time of 50% or more of the process time from when 30 wt.% of the total distillate of (B) is distillated until when 90 wt.% of the total distillate of (B) is distillated, and a pressure (B) in the gas-phase of the distillation step is P2 which satisfies the condition 2. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

4 phosphoric acid ester salt tertiary annular cyanoamidines

PROBLEM TO BE SOLVED: To provide a method for producing a quaternary cyclic amidine phosphoric acid ester salt in a short time.SOLUTION: The method for producing a quaternary cyclic amidine phosphoric acid ester salt comprises reacting an amine (A) represented by general formula (1), a salt (D) of a phosphoric acid ester (C) represented by general formula (2), and a diamine monoamide compound (E) represented by general formula (3) in the presence of a solvent (B) having a boiling point higher than the boiling points of the amine (A) and water and a solubility parameter of 8-25 (cal/cm)), and then causing a cyclization dehydration reaction by removing formed water to obtain a quaternary cyclic amidine phosphoric acid ester salt (F).

1,2- and 1,3-Diamine Exchange between Substituted 4,5-Dihydroimidazoles and 1,4,5,6-Tetrahydropyrimidines: Routes to Benzimidazoles, Dihydroimidazoles, and Tetrahydropyrimidines

A range of 2-substituted 4,5-dihydroimidazoles and 2-substituted 1,4,5,6-tetrahydropyrimidines when heated with an excess of substituted ethane-1,2-diamines, o-phenylenediamines, and propane-1,3-diamine underwent diamine exchange to give 2-substituted heterocycles derived from the solvent diamine.The reaction was an equilibrium process favouring six-membered rings.The synthetic scope is amplified by the ready aromatisation of these partially reduced heterocycles.