953039-15-1

Basic information

• Product Name: 2-CHLORO-7-METHOXYQUINAZOLINE
• Synonyms: 2-CHLORO-7-METHOXYQUINAZOLINE
• CAS NO: 953039-15-1
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.62
• Mol File: 953039-15-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CHLORO-7-METHOXYQUINAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-7-METHOXYQUINAZOLINE(953039-15-1)
• EPA Substance Registry System: 2-CHLORO-7-METHOXYQUINAZOLINE(953039-15-1)

Safety Data

• Hazardous Substances Data: 953039-15-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-CHLORO-7-METHOXYQUINAZOLINE is used as a building block for the synthesis of biologically active compounds and potential drug candidates. Its structure and reactivity make it a valuable intermediate in the development of new pharmaceuticals.
Used in Organic Synthesis:
In the field of organic synthesis, 2-CHLORO-7-METHOXYQUINAZOLINE is utilized as a reagent and in chemical reactions to create new compounds with diverse properties. Its versatility in forming various chemical entities makes it a useful component in the synthesis of a wide range of organic compounds.
Used in Laboratories:
2-CHLORO-7-METHOXYQUINAZOLINE is also used in laboratories for research purposes, where it serves as a reagent in various chemical experiments and reactions. Its properties and reactivity contribute to the advancement of scientific knowledge and the discovery of new chemical compounds.
Used in Anti-inflammatory and Anti-cancer Research:
2-CHLORO-7-METHOXYQUINAZOLINE has been studied for its potential anti-inflammatory and anti-cancer properties. Its ability to modulate biological processes and target specific pathways makes it a promising candidate for the development of therapeutic agents in these areas.

Upstream product

• 953039-66-2 7-bromo-2-chloroquinazoline 
• 124-41-4 sodium methylate 
• 59236-36-1 2-amino-4-methoxybenzaldehyde 
• 22996-21-0 4-methoxy-2-nitro-benzaldehyde 
• 17484-36-5 4-Methyl-3-nitroanisole 
• 91099-24-0 2-hydroxy-7-methoxyquinazoline 

Downstream Products

• 953039-95-7 2-(4-(morpholine-4-sulfonyl)phenylamino)-quinazolin-7-yl trifluoromethanesulfonate 
• 953039-93-5 2-(4-morpholin-4-ylsulfonyl-phenylamino)-quinazolin-7-ol 

Relevant articles and documents

Novel FLT3 kinase inhibitor and application thereof

The invention provides a novel FLT3 kinase inhibitor. The novel FLT3 kinase inhibitor comprises a compound shown in the formula (I) or pharmacy acceptable salt or solvate or isomer or ester or acid or metabolin or prodrug. The invention also provides a pharmaceutical composition of the compound shown in the formula (I) and an application and method of the pharmaceutical composition for preventing or treating cell proliferation disease and/or FLT3 and c-Kit related disease and disease responding to FLT3 kinase ( particularly, responding to FLT3/ITD mutant kinase) inhibition.

QUINAZOLINES FOR PDK1 INHIBITION

The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.