10252-46-7Relevant articles and documents
Additive-free pd-catalyzed α-allylation of imine-containing heterocycles
Kljajic, Marko,Puschnig, Johannes G.,Weber, Hansj?rg,Breinbauer, Rolf
, p. 126 - 129 (2017)
An additive-free Pd-catalyzed α-allylation of different imino-group-ontaining heterocycles is reported. The activation of α-CH pronucleophiles (pKa (DMSO) > 25) occurs without the addition of strong bases or Lewis acids using only the Pd/Xantphos catalyst system. The reaction scope has been studied for various 5- and 6-membered nitrogen-containing heterocycles (yields up to 96%). Mechanistic investigations suggest an initial allylation of the imine-N followed by a Pd-catalyzed formal aza-Claisen rearrangement.
Unexpected ring opening of pyrazolines with activated alkynes: synthesis of 1H-pyrazole-4,5-dicarboxylates and chromenopyrazolecarboxylates
Bhimapaka, China Raju,Kolla, Sai Teja,Rayala, Nageswara Rao,Sridhar, Balasubramanian
supporting information, p. 334 - 338 (2022/01/20)
1H-Pyrazole-4,5-dicarboxylates and chromenopyrazole carboxylates were prepared by reacting pyrazolines with activated alkynes under neat conditions without a catalyst. The products were formed via unexpected ring opening of pyrazolines with the elimination of styrene/ethylene. These types of transformations are unknown and the products formed were confirmed using their spectral/analytical data. In addition, the structures of compounds 5e and 5n were confirmed by single-crystal X-ray analysis. Control experiments were conducted to support the proposed reaction mechanism.
Heterocyclization of β,γ-unsaturated onium compounds of phosphorus and nitrogen under the action of phenylhydrazine
Ovakimyan,Gasparyan,Pogosyan,Movsisyan,Indzhikyan,Panosyan
experimental part, p. 1891 - 1893 (2011/02/27)
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