10400-19-8Relevant articles and documents
Catalytic and electrocatalytic wet oxidation of phenol using two new nickel(II) tetraazamacrocycle complexes under heterogeneous conditions
Bansal, Vipin Kumar,Thankachan, Pompozhi Protasis,Prasad, Rajendra
, p. 131 - 138 (2010)
Two new tetraazamacrocycle complexes, namely, 7,16-dinicotinoyl[Ni{Me4(4-MeBzo)2[14]tetraeneN4}] and 7,16-diisonicotinoyl[Ni{Me4(4-MeBzo)2[14]tetraeneN4}] (where [Ni{Me4(4-MeBzo)
Palladium(II)-catalysed oxidation of alcohols under an oxygen atmosphere in a fluorous biphase system (FBS)
Nishimura, Takahiro,Maeda, Yasunari,Kakiuchi, Nobuyuki,Uemura, Sakae
, p. 4301 - 4305 (2000)
Palladium(II) acetate catalyses the aerobic oxidation of alcohols into the corresponding aldehydes and ketones in the presence of a catalytic amount of a novel perfluoroalkylated-pyridine as a ligand using molecular oxygen in a fluorous biphase system (FBS) composed of toluene and perfluorodecalin. This catalytic system is applicable to various benzylic and aliphatic alcohols. The fluorous phase containing the active palladium species is easily separated and can be reused several times without a significant loss of catalytic activity. The Royal Society of Chemistry 2000.
Crystal structure and energy optimization of dichlorobis(ethylanthranilatonicotinamide)zinc(II)
Narayanan, Venkatraj V.,Gopalan, R. Srinivasa,Chakrabarty, Debojit,Mobin, Shaikh M.,Mathur, Pradeep
, p. 801 - 805 (2011)
The title compound, C30H28Cl2N 4O6Zn, dichlorobis(ethylanthranilatonicotinamide)zinc(II) crystallized in a triclinic space group, P - 1, with cell parameters a = 7.787(3), b = 13.468(1), c = 15.735(1)
Anion templated surface assembly of a redox-active sensory rotaxane
Bayly, Simon R.,Gray, Thomas M.,Chmielewski, Michal J.,Davis, Jason J.,Beer, Paul D.
, p. 2234 - 2236 (2007)
Anion templation is used to assemble novel redox-active bis-ferrocene functionalised rotaxane self-assembled monolayers (SAMs) on to gold electrode surfaces; after template removal, the unique SAM rotaxane binding domain is capable of selectively sensing chloride ions electrochemically. The Royal Society of Chemistry.
Fluorescent hydrogels formed by CH-π and π-π Interactions as the main driving forces: An approach toward understanding the relationship between fluorescence and structure
Ahn, Jinho,Park, Sunhong,Lee, Ji Ha,Jung, Sung Ho,Moon, Seung-Jin,Jung, Jong Hwa
, p. 2109 - 2111 (2013)
Amide-linked tripyridine derivatives 1, with a para-substituent, and 2, with a meta-substituent, were gelated in water or water-DMSO. The gelation capabilities of 1 and 2 were attributed to the cooperative effects of mainly CH-π and π-π stacking or strong intermolecular hydrogen bonding interactions between the amide groups. The fluorescence properties of gels 1 and 2 were dependent on the binding strength of the π-π stacking.
Polymeric complexes with "piperazine-pyridine" building blocks: Synthesis, network structures, and third-order nonlinear optical properties
Hou, Hongwei,Song, Yinglin,Xu, Hong,Wei, Yongli,Fan, Yaoting,Zhu, Yu,Li, Linke,Du, Chenxia
, p. 999 - 1008 (2003)
A new bidentate "building block", N,N′-bis(3-pyridylformyl)piperazine (bpfp), was synthesized. X-ray diffraction studies reveal that the piperazine ring in bpfp forms a chairlike structure conformation, bpfp self-assembled into two-dimensional layered rhombohedral grid polymers {[Mn(H2O)2(SO4)(bpfp)](H2O)3 (CH3OH)}n (1) and {[Zn(NCS)2(bpfp)2]·2H2O}n (2) with Mn(II) and Zn(II), a three-dimensional polymer [Cd(N3)2(bpfp)]n (3) with Cd(II), and a one-dimensional zigzag polymer [HgI2(bpfp)]n (4) with Hg(II). Each rhombohedral grid in polymer 1 is composed of four Mn, two bpfp, and two SO42-; the dimensions of the grid are 6.537 × 12.843 A. In polymer 2, each rhombohedral grid consists of 60-membered rings Zn4(bpfp)4 showing the dimensions of 14.231 × 15.586 A. Zn4(bpfp)4 grids are bridged by Zn ions and all pyridyl-N atoms of bpfp ligands into the 2-D network structure along a and c directions. Polymer 3 exhibits a 3-D layered structure with tetragonal prism channel viewing from a direction. The bpfp ligands occupy the four edges of tetragonal prism channel, which is cut off by layers consisting of rhombohedral grids Cd4(N3)4. Polymer 4 is quite different from polymers 1-3; it exhibits a 1-D zigzag framework extending along the c axis. Polymers 1-3 possess a very strong NLO absorption and self-focusing effect. Their third-order NLO absorptive coefficients α2 are 9.2 × 10-9, 6.9 × 10-9, and 7.1 × 10-9 m W-1. The third-order NLO hyperpolarizabilities γ are 1.79 × 10-28, 9.10 × 10-29, and 9.66 × 10-29 esu, respectively. The γ values are comparable to those of the best NLO materials and coordination polymers. We found that the valence shell structures of central metal ions can influence the NLO properties of coordination polymers.
Phase transfer-catalyzed, one-pot synthesis of some novel N-pyrimidinyl-N'-nicotinyl thiourea derivatives
Liu, Xing-Hai,Tan, Cheng-Xia,Weng, Jian-Quan
, p. 552 - 557 (2011)
A new series of acyl thiourea derivatives were synthesized in one-pot using PEG-600 as the phase transfer catalyst (PTC). The structures of title compounds were characterized by 1H NMR, IR, MS, and elemental analysis. In addition, the fungicidal activity of the acyl thiourea derivatives were tested, which showed that most of them exhibit moderate activity. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
Design, synthesis, and vasorelaxation activity of novel imperatorin derivatives
Zhou, Nan,He, Jian-Yu,Wang, Tao,Zhang, Jie,He, Huai-Zhen
, p. 650 - 657 (2013)
In this study, a series of novel imperatorin derivatives 7a-7e were designed and synthesized. Their vasorelaxation activities were evaluated by the pharmacological experiments in vitro. Most of the tested compounds exhibited better water solubility and vasorelaxation activity in different degrees, especially 7b and 7c with EC50 values of 2.29 and 2.63 μM, respectively on mesenteric artery, 7d and 7e with EC50 values of 1.04 and 2.65 μM, respectively on brain artery. The results indicated that these novel compounds have a potential interest for the development of novel and potent vasorelaxant agents for different kinds of arteries.
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Wingfield et al.
, p. 4364 (1953)
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Pseudocryptand Hosts for Paraquats and Diquats
Jones, Jason W.,Price, Terry L.,Huang, Feihe,Zakharov, Lev,Rheingold, Arnold L.,Slebodnick, Carla,Gibson, Harry W.
, p. 823 - 834 (2018)
H-bonding interaction of acidic moieties (CH2OH, COOH) at the 5- and 5′-positions of bis(1,3-phenylene)-32-crown-10 (1) with di- or tritopic anions leads to enhanced formation of inclusion complexes with N,N′-dialkyl-4,4′-bipyridinium salts ("paraquats", 2); the enforced folding of the crown ethers into pseudocryptands thus leads to pseudo-pseudorotaxanes. Strikingly, in the presence of the most effective anion (trifluoroacetate, TFA), the apparent bimolecular association constants for crown-paraquat complexation increase by more than an order of magnitude and approach those for covalent cryptands derived from the crown ether. Even though they may form pseudocryptands, the picolinate, nicotinate, and isonicotinate diesters 6 of cis-(4,4')-bis(hydroxymethyl)dibenzo-30-crown-10 do not exhibit enhanced binding of either diquat or paraquat relative to the starting diol in contrast to the picolinate ester of isomeric 5,5′-bis(hydroxymethyl)bis(m-phenylene)-32-crown-10, which displayed a higher binding constant than the starting diol. The results for the analogous reverse esters 7 derived from cis-(4,4')-dicarboxydibenzo-30-crown-10 and pyridylmethanols reveal weaker complexes with diquat than the normal esters 6; however, surprisingly, two reverse esters 7 complex paraquat more strongly than isomers 6.
Synthesis of sugar modified nucleosides containing nicotinic, quinaldic, indol-3-ylpropionic or 1-nitroanthraquinone-2-carboxylic acid residue
Melnik,Ektova,Goryunova,Khorysheva,Makutova,Plikhtyak,Yartseva
, p. 377 - 380 (1995)
The nucleoside derivatives were synthesized with arylcarbonic acid residue as an anchor group at the sugar moiety coupled by an ester or an amide bond. Their cytotoxic properties and effects on DNA structure were studied.
Prodrug compound and application thereof in treatment of cancer
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Paragraph 0132-0133, (2021/03/06)
The present invention provides a compound indicated by a formula (I), pharmaceutically acceptable salts or esters thereof, a pharmaceutical composition of the compound, and the use of the compound andthe pharmaceutical composition in inhibition or regulation of tyrosine kinase activity, and treatment of tyrosine kinase mediated disease symptoms or disorders including cancer.
Metathesis-active ligands enable a catalytic functional group metathesis between aroyl chlorides and aryl iodides
Lee, Yong Ho,Morandi, Bill
, p. 1016 - 1022 (2018/09/06)
Current methods for functional group interconversion have, for the most part, relied on relatively strong driving forces which often require highly reactive reagents to generate irreversibly a desired product in high yield and selectivity. These approaches generally prevent the use of the same catalytic strategy to perform the reverse reaction. Here we describe a catalytic functional group metathesis approach to interconvert, under CO-free conditions, two synthetically important classes of electrophiles that are often employed in the preparation of pharmaceuticals and agrochemicals—aroyl chlorides (ArCOCl) and aryl iodides (ArI). Our reaction design relies on the implementation of a key reversible ligand C–P bond cleavage event, which enables a non-innocent, metathesis-active phosphine ligand to mediate a rapid aryl group transfer between the two different electrophiles. Beyond enabling a practical and safer approach to the interconversion of ArCOCl and ArI, this type of ligand non-innocence provides a blueprint for the development of a broad range of functional group metathesis reactions employing synthetically relevant aryl electrophiles.
