10409-54-8Relevant articles and documents
REACTION OF ALDEHYDES AND KETONES WITH t-BUTYL BROMIDE-DIMETHYL SULPHOXIDE
Armani, E.,Dossena, A.,Marchelli, R.,Casnati, G.
, p. 2035 - 2040 (1984)
Reacting aldehydes and ketones with the "ButBr-Me2SO" system produces the corresponding α-bromoderivatives 2.In the case of ketones, where more than one regioisomer is possible, bromination is obtained exclusively at the more highly substituted α-position.With slight modifications of the reaction conditions (addition of Me2S, Me2SO) it is possible to obtain "in situ" formation of either dimethyl(2-oxo-phenylalkyl)sulphonium salts 3 or of α-methylthioderivatives 4.Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium bromide (3h) during crystallization undergoes spontaneous resolution of the two enantiomers, as demonstrated by single crystal X-ray analysis and absolute configuration assignment.
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De Puy,Van Lanen
, p. 3360,3361,3362 (1974)
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Synthesis and Spontaneous Resolution by Crystallization of R,S-(+/-)-Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium Bromide. X-Ray Structure and Absolute Configuration of the R-Enantiomer
Dossena, Arnaldo,Marchelli, Rosangela,Armani, Elisabetta,Fava, Giovanna Gasparri,Belicchi, Marisa Ferrari
, p. 1196 - 1197 (1983)
R,S-(+/-)-Dimethyl(1-methyl-2-oxo-2-phenylethyl)sulphonium bromide (3a), obtained from 1-phenylpropanone by bromination with t-butyl bromide-dimethyl sulphoxide and further reaction with dimethyl sulphide, undergoes spontaneous resolution of its two enantiomers upon crystallization, as demonstrated by a single crystal X-ray analysis and assignment of absolute configuration (R).
β-KETO SULFIDE COMPOUND, PHOTOCURING AGENT AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THEM
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Paragraph 0150-0153, (2021/02/25)
To provide a β-keto sulfide compound, a photocuring agent and a photosensitive resin composition.SOLUTION: There are provided a compound represented by formula (1): (In the formula, Ring A represents a benzene ring or a naphthalene ring; R1 and R2 may be the same or different and each represents a hydrogen atom, an alkyl group which may have a substituent, and the like; R3 is an alkyl group, an acyl group, an alkoxy group, and the like; n represents an integer of 0 to 5; alternatively, R3 and R1 bonded to the carbon atom constituting Ring A may be bonded to each other to form a ring, and the ring may have a substituent; R4 represents an alkylene group which may have a hydroxy group; R5 represents an alkylene group; X represents an ester group and the like; Y represents a hydrogen atom or an organic group having a valency of 1 to 6;. p represents an integer of 1 to 6; q represents 0 or 1; with the proviso that when p represents 1, q represents 1 and Y represents a hydrogen atom, and that when p represents an integer of 2 to 6, q represents 0 or 1 and Y represents an organic group having a valency of 2 to 6), and a photocuring agent containing the compound, and a photosensitive resin composition containing them.SELECTED DRAWING: None
Access to α-Cyano Carbonyls Bearing a Quaternary Carbon Center by Reductive Cyanation
Ren, Xinyi,Shen, Chaoren,Wang, Guangzhu,Shi, Zhanglin,Tian, Xinxin,Dong, Kaiwu
supporting information, p. 2527 - 2532 (2021/05/05)
Reductive cyanation of tertiary alkyl bromides using electrophilic cyanating reagent and zinc reductant was developed, providing various α-cyano ketones, esters, and carboxamides containing a nitrile-bearing all-carbon quaternary center in good to excellent yields under mild reaction conditions. The corresponding reaction mechanism involving in situ generated organozinc reagent and reactivity distinction was elucidated by density functional theory computation.