10581-12-1

Basic information

• Product Name: Tetramethylammonium acetate
• Synonyms: TETRAMETHYLAMMONIUM ACETATE;TETRAMETHYLAMMONIUM ACETATE HYDRATE;n,n,n-trimethyl-methanaminiuacetate;TETRAMETHYLAMMONIUM ACETATE, 90% TECH.;Tetramethylammonium acetate, 50% aqueous solution;METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE;Tetramethylammonium acetate, tech. 90%;Tetramethylammonium Acetate (ca. 15% in Water)
• CAS NO: 10581-12-1
• Molecular Formula: C₂H₃O₂*C₄H₁₂N
• Molecular Weight: 133.19
• EINECS: 234-179-3
• Product Categories: quarternary ammonium salts;Ammonium Polyhalides, etc. (Quaternary);Quaternary Ammonium Compounds;Ammonium Salts;Greener Alternatives: Catalysis;Phase Transfer Catalysts
• Mol File: 10581-12-1.mol

Chemical Properties

• Melting Point: 184 °C (dec.)(lit.)
• Appearance: White/Crystalline Solid
• Storage Temp.: -20°C
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• BRN: 3571830
• CAS DataBase Reference: Tetramethylammonium acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Tetramethylammonium acetate(10581-12-1)
• EPA Substance Registry System: Tetramethylammonium acetate(10581-12-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 3-10
• TSCA: Yes
• Hazardous Substances Data: 10581-12-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Tetramethylammonium acetate is used as an intermediate in organic synthesis for its ability to facilitate chemical reactions and produce desired products.
Used in Pharmaceuticals:
In the pharmaceutical industry, Tetramethylammonium acetate is used as a key component in the development of various drugs, contributing to their efficacy and safety.
Used in Agrochemicals:
Tetramethylammonium acetate plays a significant role in the agrochemical industry, where it is employed to enhance the effectiveness of pesticides and other agricultural chemicals.
Used in Dyestuffs:
The compound is also used in the dyestuffs industry to improve the quality and performance of dyes, ensuring vibrant and long-lasting colors.
Used in Preparation of Specific Compounds:
Tetramethylammonium acetate is used to prepare (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester by reacting with 1,3-dimethyl-imidazolidin-2-one, showcasing its versatility in chemical reactions.
Used as an Emulsifier:
In various industries, Tetramethylammonium acetate is used as an emulsifier to stabilize mixtures and improve the texture of products.
Used as a Catalyst:
The compound serves as a catalyst to speed up chemical reactions, increasing the efficiency of production processes.
Used as a Sterilizer:
Tetramethylammonium acetate is employed as a sterilizer to ensure the cleanliness and safety of products in various applications.
Used as an Antistatic Agent:
It is used as an antistatic agent to reduce the buildup of static electricity in materials, which can be crucial in sensitive environments.
Used as an Antiseptic Agent:
Tetramethylammonium acetate is also used as an antiseptic agent to prevent the growth of harmful microorganisms and maintain product integrity.

InChI:InChI=1/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;

Upstream product

• 631-61-8 ammonium acetate 
• 616-38-6 carbonic acid dimethyl ester 
• 6998-30-7 methylamine acetate 
• 75-59-2 tetramethyl ammoniumhydroxide 
• 64-19-7 acetic acid 

Downstream Products

• 40752-00-9 N-mesityl-N-methylacetamide 
• 40752-06-5 N-Mesityl-N-(methyl)-aminomethyl-acetat 
• 426225-93-6 (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester 
• 116143-06-7 4-(acetyloxy)-1-<(4-methylphenyl)sulfonyl>-D-proline ethyl ester 
• 30315-04-9 Acetic acid (3aR,6aR,7aS,8R,10S,11aS,11bS,11cS)-2-methoxy-3,8,11a,11c-tetramethyl-1,5,11-trioxo-1,3a,4,5,6a,7,7a,8,9,10,11,11a,11b,11c-tetradecahydro-6-oxa-benzo[de]anthracen-10-yl ester 
• 26775-14-4 3-O-acetyl-1,2:5,6-di-O-isopropylidene-α-D-gulofuranose 
• 2774-28-9 3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-erythro-hex-3-enofuranose 
• 67601-06-3 (3S,6R)-3-methyl-6-(1-methylethenyl)-9-decen-1-yl acetate 
• 97645-14-2 2-carbomethoxy-2-(4-acetoxy-3-(phenylthio)-(E)-butenyl)-1-cyclopentanone 
• 3067-12-7 benzo[a]pyrene-6,12-dione 
• 53555-67-2 benzopyren-6-yl acetate 
• 3067-13-8 benzo[a]pyrene-1,6-quinone 
• 3067-14-9 benzo[a]pyrene-3,6-dione 
• 2381-39-7 6-Methylbenzopyrene 

Relevant articles and documents

Therapeutic delivery of carbon monoxide

Compounds, pharmaceutical compositions and methods for the therapeutic delivery of carbon monoxide to humans and other mammals that employ Mn complexes having CO ligands, and additional halogen, monodentate and/or bidentate ligands, wherein the additional ligands do not occupy trans positions relative to each other.

POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS

A positive resist composition comprises (A) a resin component which becomes soluble in an alkaline developer under the action of an acid and (B) an acid generator. The resin (A) is a polymer comprising recurring units containing a non-leaving hydroxyl group represented by formula (1) wherein R1 is H, methyl or trifluoromethyl, X is a single bond or methylene, m is 1 or 2, and the hydroxyl group attaches to a secondary carbon atom. The composition is improved in resolution when processed by lithography.

Alkylation of ammonium salts catalyzed by imidazolium-based ionic liquid catalysts

Quaternary ammonium salts were synthesized from ammonium salts and dialkyl carbonates over imidazolium ionic liquid catalysts. The reaction gave almost stoichiometric amounts of the quaternary ammonium salts for halides and nitrates. It was found that the electron-donating property of the alkyl moieties of ammonium cations, the electrophilic nature of the alkyl group of the carbonate, the acidity of the acid that the anion of the ammonium salt corresponds to, and the steric hindrance of the ammonium salts and the dialkyl carbonates are the key factors that influence the yields of quaternary ammonium salts. Strong electron-donating alkyl groups on the nitrogen atom of the ammonium salt, electron-withdrawing groups on the methylene carbon of dialkyl carbonate, and weaker steric hindrance of the starting ammonium salts and dialkyl carbonates favor the alkylation reaction of ammonium salts.

The synthesis of quaternary ammonium salts from ammonium salts and dialkyl carbonate

Quaternary ammonium salts were synthesized from ammonium salts and dialkyl carbonates over an ionic liquid catalyst 1-ethyl-3-methylimidazolium bromide. The Royal Society of Chemistry 2006.

Process for the hydrogenation of nitrated paraffins using a palladium on carbon catalyst characterized by a low ash and a low halide content

Nitrated hydrocarbons, such as nitroparaffins, are reduced to amines by use of palladium on a carbon catalyst characterized by low ash and low halide.