118591-58-5Relevant articles and documents
Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors
Sadrerafi, Keivan,Mason, Emilia O.,Lee, Mark W.
, p. 987 - 995 (2018)
Purpose: Our previous study indicated that carborane containing small-molecule 1-(hydroxymethyl)-7-(4′-(trans-3″-(3′″-pyridyl)acrylamido)butyl)-1,7-dicarbadodecaborane (hm-MC4-PPEA), was a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt)
Gold nanoparticles coated with semi-fluorinated oligo(ethylene glycol) produce sub-100 nm nanoparticle vesicles without templates
Niikura, Kenichi,Iyo, Naoki,Higuchi, Takeshi,Nishio, Takashi,Jinnai, Hiroshi,Fujitani, Naoki,Ijiro, Kuniharu
, p. 7632 - 7635 (2012)
Gold nanoparticles (NPs) with diameters of 5, 10, and 20 nm coated with semifluorinated oligo(ethylene glycol) ligands were formed into sub-100 nm hollow NP assemblies (NP vesicles) in THF without the use of a template. The NP vesicles maintained their st
Synthesis of optically active 1,1′-binaphthyl-phthalocyanines linked via a crown ether unit
Liu, Hong-Wei,Chen, Chuan-Fu,Ai, Min,Gong, Ai-Jun,Jiang, Jing,Xi, Fu
, p. 4915 - 4922 (2000)
Novel optically active metal and metal-free phthalocyanines, substituted with 1,1′-binaphthyl crown ether units, have been synthesized and characterized.
Closing the Loop: Triazolylpyridine Coordination Drives the Self-Assembly of Metallomacrocycles with Tunable Topologies for Small-Molecule and Guanine-Quadruplex Recognition
Miron, Caitlin E.,Colden Leung, Madelaine R.,Kennedy, Emily I.,Fleischel, Olivier,Khorasani, Mona Ashraf,Wu, Nan,Mergny, Jean-Louis,Petitjean, Anne
, p. 18718 - 18734 (2018)
The 2-(1,2,3-triazol-4-yl)pyridine motif, with its facile “click” synthesis and remarkable coordinative properties, is an attractive chelate for applications in the metal-directed self-assembly of intricate three-dimensional structures. Organic ligands th
HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS
-
Paragraph 0259-0260; 0323-0324, (2021/09/11)
The invention relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
Fluorescent Columnar Liquid-Crystalline Polymers: Synthesis, Mesomorphic Behaviors and Tunable Emission Wavelengths?
Hao, Xiangnan,Mu, Bin,Tian, Wei,Zhang, Zhelin,Zhao, Yu
supporting information, p. 2009 - 2015 (2021/06/08)
Fluorescent columnar liquid-crystalline polymers have attracted intensive attention due to their unique features that can be applied in many fields. However, the utilization of molecular engineering to achieve efficient fluorescence tuning has rarely been
Supramolecular compound nano-carrier as well as preparation method and application thereof
-
Paragraph 0068; 0082, (2021/08/14)
The invention discloses a supramolecular compound nano-carrier as well as a preparation method and application thereof, and relates to the technical field of polymer chemistry and biological detection engineering. According to the supramolecular compound nano-carrier disclosed by the invention, a two-dimensional nanosheet supramolecular structure system generated by self-assembly is driven by an anion induction effect, and a supramolecular compound nano-carrier is of a single-layer nanosheet supramolecular structure constructed by a highly-oriented one-dimensional nanorod. A hydrophobic perylene group part is used as a skeleton part for constructing the highly-oriented one-dimensional nanorod, and the charge density of a single-layer nanosheet can be regulated and controlled. The surface of the water-soluble multivalent hydrophilic part can be loaded with DNAzyme deoxyribozyme for specific detection of heavy metal ions through electrostatic interaction, and the water-soluble multivalent supramolecular compound nano sensor is constructed. Based on a fluorescence change mechanism caused by specific cutting of heavy metal ions, The fluorescence detection of the heavy metal ions in food and biological tissues is realized, and the detection effect of the heavy metal ions is greatly enhanced.