13063-60-0

Basic information

• Product Name: 4-octylmorpholine
• Synonyms: 4-octylmorpholine;Einecs 235-957-5;Morpholine, 4-octyl-
• CAS NO: 13063-60-0
• Molecular Formula: C₁₂H₂₅NO
• Molecular Weight: 199.333
• EINECS: 235-957-5
• Mol File: 13063-60-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 265.7°Cat760mmHg
• Flash Point: 77.9°C
• Appearance: /
• Density: 0.885g/cm³
• Vapor Pressure: 0.00901mmHg at 25°C
• Refractive Index: 1.451
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-octylmorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-octylmorpholine(13063-60-0)
• EPA Substance Registry System: 4-octylmorpholine(13063-60-0)

Safety Data

• Hazardous Substances Data: 13063-60-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H25NO/c1-2-3-4-5-6-7-8-13-9-11-14-12-10-13/h2-12H2,1H3

Upstream product

• 5338-65-8 octanoic acid, morpholide 
• 111-86-4 n-Octylamine 
• 111-46-6 diethylene glycol 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 31866-75-8 N-hexyl morpholine 
• 110-91-8 morpholine 
• 111-87-5 octanol 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 111-83-1 1-bromo-octane 
• 629-05-0 n-octyne 
• 155127-38-1 ((E)-4-Oct-1-enyl)-morpholine 
• 82394-18-1 1,4-diheptylpiperazine 
• 544-10-5 1-Chlorohexane 
• 543-59-9 1-Chloropentane 

Downstream Products

• 25727-94-0 4-decylmorpholine 
• 2473-01-0 1-Chlorononane 
• 1002-69-3 decyl chloride 
• 111-85-3 n-chlorooctane 

Relevant articles and documents

Ruthenium Complex Catalyzed N-Heterocyclization. Syntheses of N-Substituted Piperidines, Morpholines, and Piperazines from Amines and 1,5-Diols

1,5-Pentanediol reacts with aliphatic and aromatic primary amines in the presence of a ruthenium catalyst modified with phosphonic ligands to give N-substituted piperidines in fair to goods yields.The reactions were carried out at 150-180 deg C for 5 h in dioxane.The nature of the phosphorus ligands has a remarkable effect on the catalytic activity, For the reaction of aromatic amines, triphenylphosphine is effective, while for aliphatic amine more basic tributyl- or triethylphosphine is preferable.Amines also react with diethylene glycol and N-substituted diethanolamines in the presence of the ruthenium catalyst to give N-substituted morpholines and piperazines in good yields, respectively.

Colloid and Nanosized Catalysts in Organic Synthesis: XVIII.1 Disproportionation and Cross-Coupling of Amines During Catalysis with Immobilized Nickel Nanoparticles

It has been stated that immobilized nickel nanoparticles catalyze disproportionation and cross-coupling of amines. The influence of the support on the catalysis of these properties in the in plug-flow reactor has been studied. The use of active carbon as the support has been found advantageous for the cross-coupling of amines, whereas alumina was a better support for the disproportionation reaction.

Base-promoted N-alkylation using formamides as the N-sources in neat water

An efficient catalyst-free, alternative method for the C-N bond formation reaction of alkyl electrophiles using formamides as the N-sources was achieved under mild conditions. The reaction possesses the advantages of a broad range of substrates scope and wide functional group tolerance. It should also be noted that this process was performed using the environmentally benign water as the sole solvent, and high yield can also be achieved in ten-gram scale.