140860-51-1

Basic information

• Product Name: (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID
• Synonyms: (-)-(1S,4R)-GAMMA-HOMOCYCLOLEU-2-ENE;2-Bromo-4-methoxybenzonitrile;2-Bromo-4-methoxy-carbonitrile
• CAS NO: 140860-51-1
• Molecular Formula: C₈H₆BrNO
• Molecular Weight: 127.14
• Mol File: 140860-51-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 139.3 °C
• Boiling Point: 312.8±27.0 °C(Predicted)
• Appearance: /
• Density: 1.56
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID(140860-51-1)
• EPA Substance Registry System: (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID(140860-51-1)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 36/37/39-26-22
• Hazardous Substances Data: 140860-51-1(Hazardous Substances Data)

Usage

General Description

(-)-(1S,4R)-4-aminocyclopent-2-enecarboxylic acid is a chemical compound with the molecular formula C6H9NO2. It is a cyclopentene derivative with a carboxylic acid group and an amino group attached to the carbon ring. The compound exists as a chiral molecule, with the (1S,4R) configuration determining its stereochemistry. It is often used as a building block in the synthesis of various pharmaceuticals and other organic compounds. The compound's structure and properties make it an important intermediate in organic chemistry, with potential applications in drug development and other industries.

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 43192-31-0 2-bromo-4-methoxybenzaldehyde 
• 2398-37-0 3-methoxyphenyl bromide 
• 36282-26-5 2-bromo-4-fluorobenzonitrile 
• 124-41-4 sodium methylate 
• 7507-86-0 2-bromo-5-methoxy-benzaldehyde 
• 186581-53-3 diazomethane 
• 82380-17-4 2-bromo-4-hydroxybenzonitrile 

Downstream Products

• 21883-13-6 4-methoxy-2-methylbenzonitrile 
• 26829-43-6 6-methoxy-2H-isoquinolin-1-one 
• 82380-17-4 2-bromo-4-hydroxybenzonitrile 

Relevant articles and documents

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

The Fujiwara-Moritani reaction has had a profound contribution in the emergence of contemporary C-H activation protocols. Despite the applicability of the traditional approach in different fields, the associated reactivity and regioselectivity issues had

Palladium-catalyzed highly selective ortho-halogenation (I, Br, Cl) of arylnitriles via sp2 C-H bond activation using cyano as directing group

A palladium-catalyzed ortho-halogenation (I, Br, Cl) of arylnitrile is described. The optimal reaction conditions were identified after examining various factors such as catalyst, additive, solvent, and reaction temperature. Using cyano as the directing group, the halogenation reaction gave good to excellent yields. The method is compatible to the arylnitriles with either electron-withdrawing or electron-donating groups. The reaction is available to the substrate in at least gram scale. The present method was successfully applied to the synthesis of the precursors of paucifloral F and isopaucifloral F.

Synthesis of C-linked immobilized analogs of aloisine A by 'click' chemistry

An efficient approach for the immobilization of a series of analogs of aloisine A, an in vitro inhibitor of protein kinases, to polymeric supports via a [3+2] cycloaddition reaction is reported.