147514-19-0

Basic information

• Product Name: Benzene, [(1S)-2-bromo-1-methylethyl]-
• Synonyms: (S)-(β-Brom-isopropyl)-benzol;2(S)-phenylpropyl-1-bromide;((S)-2-Bromo-1-methyl-ethyl)-benzene;(S)-1-bromo-2-phenylpropane;(-)(S)-1-Brom-2-phenyl-propan;(S)-2-phenyl-1-bromopropane;(-)(S)-1-bromo-2-phenyl-propane
• CAS NO: 147514-19-0
• Molecular Formula: C9H11Br
• Molecular Weight: 199.09
• Mol File: 147514-19-0.mol

Chemical Properties

• Boiling Point: 100 - 103 °C (12 mmHg)
• Density: 1.303±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, [(1S)-2-bromo-1-methylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1S)-2-bromo-1-methylethyl]-(147514-19-0)
• EPA Substance Registry System: Benzene, [(1S)-2-bromo-1-methylethyl]-(147514-19-0)

Safety Data

• Hazardous Substances Data: 147514-19-0(Hazardous Substances Data)

Upstream product

• 1123-85-9 (RS)-2-phenyl-1-propanol 
• 104266-89-9 (S)-4-benzyl-3-phenylacetyl-2-oxazolidinone 
• 170856-71-0 3-(1-oxo-2(S)-phenylpropyl)-4(S)-(phenymethyl)-2-oxazolidinone 
• 7782-24-3 (S)-2-Phenylpropionic acid 
• 286967-31-5 2(S)-phenyl-1-propanol methanesulfonate 
• 37778-99-7 (S)-2-phenyl-1-propanol 
• 74669-73-1 2-phenylpropyl 4-methylbenzenesulfonate 

Downstream Products

• 147426-12-8 (2R,4S,5S)-5-<(tert-butyloxycarbonyl)amino>-6-cyclohexyl-4-hydroxy-2-phenylhexane 
• 471241-34-6 diethyl 2-[(R)-2-phenylpropyl]-2-ethylmalonate 
• 286967-32-6 1-trimethylsilyloxy-3(S)-[2(S)-phenyl-1-propyl]-5-(R)-methyl-1-cyclohexene 
• 848413-15-0 (2RS,4R)-2-methyl-4-phenylpentanoic acid 
• 197568-73-3 (2S,3S,5R)-2-Amino-1-cyclohexyl-5-phenyl-hexan-3-ol 
• 147426-13-9 (4S,5S)-4-Cyclohexylmethyl-5-((R)-2-phenyl-propyl)-oxazolidin-2-one 
• 147426-14-0 (2R,4S,5S)-6-cyclohexyl-4-hydroxy-2-phenyl-5-<(2',2',2'-trichloro-1',1'-dimethylethoxycarbonyl)amino>hexane 
• 147426-15-1 (2R,4S,5S)-4-<(tert-butyldimethylsilyl)oxy>-6-cyclohexyl-2-phenyl-5-<(2',2',2'-trichloro-1',1'-dimethylethoxycarbonyl)amino>hexane 
• 147426-11-7 2(S)-phenylpropylmagnesium bromide 
• 1067649-13-1 3-((R)-1-hydroxy-3-phenyl-butyl)-5-(methanesulphonyl-methyl-amino)-benzoic acid methyl ester 
• 1067649-18-6 3-((R)-1-hydroxy-3-phenyl-butyl)-5-(methanesulphonyl-methyl-amino)-benzoic acid 
• 1067649-16-4 3-(methanesulphonyl-methyl-amino)-5-[(R)-1-(2-methoxy-ethoxy)-3-phenyl-butyl]-benzoic acid 
• 16433-43-5 (R)-4-phenylpentanoic acid 
• 1612882-49-1 C₁₄H₁₈O₄ 

Relevant articles and documents

Diastereoselective noncovalent synthesis of hydrogen-bonded double-rosette assemblies

Chiral centers present either in the dimelamine components of calix[4]arene 1 or in the cyanurate components CA quantitatively induce one handedness (P or M) in the corresponding hydrogen-bonded assemblies 13·(CA)6 (de>98%). The high degree of chiral induction results from the presence of six chiral centers in close proximity (Cα) to the core of the assembly. A much lower level of chiral induction is observed for assemblies with chiral centers that are more remote (Cβ). All diastereomerically pure assemblies 13·(CA)6 exhibit very high CD activities (|Δεmax|～100 L mol-1cm-1), in sharp contrast to the low CD activities (|Δεmax|≤8 L mol-1cm-1) shown by the free components. The assemblies display spontaneous resolution under thermo-dynamically controlled conditions (i.e., heteromeric assemblies containing both peripheral R and S centers are not observed. Remarkable assembly behavior is observed if both components 1 and CA are chiral. In general, formation of well-defined assemblies is only observed when both components contain unidirectional information for the induction of either M or P chirality.

A Short Stereocontrolled Synthesis of Hydroxyethylene Dipeptide Isosteres

A stereocontrolled synthesis of protected hydroxyethylene dipeptide isosteres 14 and 16 is described.It provides the 2R,4S,5S epimers required for the preparation of aspartic proteinase inhibitors.The choice of a benzene ring as a precursor to the carboxy