14814-17-6

Basic information

• Product Name: (4-(2-hydroxyethoxy)phenyl)(phenyl)methanone
• Synonyms: (4-(2-hydroxyethoxy)phenyl)(phenyl)methanone;Methanone, [4-(2-hydroxyethoxy)phenyl]phenyl-
• CAS NO: 14814-17-6
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.26986
• Mol File: 14814-17-6.mol

Chemical Properties

• Melting Point: 79-80 °C(Solv: heptane (142-82-5))
• Boiling Point: 421.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.178±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Dichloromethane, DMSO, Methanol
• PKA: 14.14±0.10(Predicted)
• CAS DataBase Reference: (4-(2-hydroxyethoxy)phenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(2-hydroxyethoxy)phenyl)(phenyl)methanone(14814-17-6)
• EPA Substance Registry System: (4-(2-hydroxyethoxy)phenyl)(phenyl)methanone(14814-17-6)

Safety Data

• Hazardous Substances Data: 14814-17-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(4-(2-Hydroxyethoxy)phenyl)(phenyl)methanone is used as an intermediate in the synthesis of E-Ospemifene (O703005) for its role in lowering serum cholesterol. E-Ospemifene, the E-isomer of Ospemifene (O703000), exhibits anti-atherosclerotic properties and has estrogen-like effects, making it a valuable compound in the development of treatments for conditions related to cholesterol and cardiovascular health.
Additionally, this compound may have potential applications in other areas of the pharmaceutical industry, depending on its specific chemical properties and reactivity, which could be further explored for the development of new drugs and therapies.

Upstream product

• 1137-42-4 4-Hydroxybenzophenone 
• 107-07-3 2-chloro-ethanol 
• 75230-42-1 1-acetoxy-2-(4-benzoylphenoxy)ethane 
• 1892-43-9 2-(4-chlorophenoxy)ethanol 
• 100-47-0 benzonitrile 
• 34743-88-9 2-(4-bromophenoxy)ethanol 
• 96-49-1 [1,3]-dioxolan-2-one 
• 75-21-8 oxirane 
• 540-51-2 2-bromoethanol 
• 98-88-4 benzoyl chloride 
• 6192-44-5 2-phenoxyethyl acetate 
• 335591-82-7 4-[2-(tert-butyldimethylsilyloxy)ethoxy]benzophenone 
• 191332-05-5 2-(4-benzoylphenoxy)ethyl tetrahydro-2H-pyran-2-yl ether 

Downstream Products

• 916170-72-4 2-({4-[Phenyl(3,3,5,5-tetramethylcyclohexylidene)methyl]phenyl}oxy)ethanol 
• 22421-66-5 2-propenoic acid 2-(4-benzoylphenoxy)ethyl ester 
• 1197029-47-2 methyl 6-hydroxy-2-(4-(2-hydroxyethoxy)phenyl)-2-phenyl-2H-naphtho[1,2-b]pyran-5-carboxylate 
• 1197029-49-4 methyl 6-(2-bromo-2-methylpropanoyloxy)-2-(4-(2-(2-bromo-2-methylpropanoyloxy)ethoxy)phenyl)-2-phenyl-2H-naphtho[1,2-b]pyran-5-carboxylate 
• 869796-85-0 1-(4-(2-hydroxyethoxy)phenyl)-1-phenylprop-2-yn-1-ol 
• 1602487-46-6 2-(4-benzoylphenoxy)ethyl benzoate 
• 128607-22-7 ospemifene 
• 1602487-47-7 (Z)-2-(4-(4-chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl benzoate 
• 1602487-45-5 2-(4-benzoylphenoxy)ethyl pivalate 
• 1601484-80-3 (Z)-2-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethyl pivalate 

Relevant articles and documents

Synthesis of lithium ω-(m- and p-lithiophenoxy)alkoxides modified with magnesium 2-ethoxyethoxide. Crystal structures of bis[4-(2-hydroxyethoxy)phenyl]mercury and bis[4-(3-hydroxypropoxy)phenyl]mercury

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