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15573-67-8

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15573-67-8 Usage

Description

4-Hydroxyphenylglyoxylic acid is a chemical compound with the molecular formula C8H6O4, belonging to the phenylglyoxylic acid derivatives. It features a hydroxyl group attached to the phenyl ring, which endows it with potential biological properties and applications in various fields.

Uses

Used in Pharmaceutical Industry:
4-Hydroxyphenylglyoxylic acid is used as an enzyme inhibitor for its ability to inhibit enzymes involved in the biosynthesis of neurotransmitters, such as tyrosine hydroxylase and phenylalanine hydroxylase. This makes it a potential candidate for the development of drugs targeting neurological disorders.
Used in Organic Synthesis:
4-Hydroxyphenylglyoxylic acid is used as a building block in the synthesis of pharmaceutical compounds, contributing to the creation of new drugs with therapeutic potential.
Used in Dye Industry:
4-Hydroxyphenylglyoxylic acid is used as a building block for dyes, owing to its chemical structure that can be modified to produce a range of colorants for various applications.
Used in Agrochemical Industry:
4-Hydroxyphenylglyoxylic acid is utilized as a building block for agrochemicals, potentially contributing to the development of new pesticides or other agricultural chemicals.
Used in Fine Chemicals Industry:
4-Hydroxyphenylglyoxylic acid is employed as a building block for fine chemicals, which are high-purity, specialty chemicals used in various industries, including pharmaceuticals, fragrances, and flavorings.

Check Digit Verification of cas no

The CAS Registry Mumber 15573-67-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,5,7 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 15573-67:
(7*1)+(6*5)+(5*5)+(4*7)+(3*3)+(2*6)+(1*7)=118
118 % 10 = 8
So 15573-67-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H6O4.Na/c9-6-3-1-5(2-4-6)7(10)8(11)12;/h1-4,9H,(H,11,12);/q;+1/p-1

15573-67-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxyphenylglyoxylic acid

1.2 Other means of identification

Product number -
Other names (4-hydroxyphenyl)(oxo)acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15573-67-8 SDS

15573-67-8Relevant articles and documents

ONE-STEP SYNTHESIS OF α-HYDROXY ACIDS VIA REDUCTIVE DOUBLE CARBONYLATION OF ORGANIC HALIDES

Kobayashi, Toshi-aki,Sakakura, Toshiyasu,Tanaka, Masato

, p. 2721 - 2722 (1987)

Palladium-catalyzed carbonylation of organic halides with water in the presence of calcium hydroxide or lithium hydroxide in primary or secondary alcoholic solvents afforded α-hydroxy acids.

Synthesis of α-Keto Acids via Oxidation of Alkenes Catalyzed by a Bifunctional Iron Nanocomposite

Song, Tao,Ma, Zhiming,Wang, Xiaoxue,Yang, Yong

supporting information, p. 5917 - 5921 (2021/07/31)

An efficient methodology for synthesis of α-keto acids via oxidation of alkenes using TBHP as oxidant catalyzed by a bifunctional iron nanocomposite has been established. A variety of alkenes with different functional groups were smoothly oxidized into their corresponding α-keto acids in up to 80% yield. Moreover, the bifunctional iron nanocomposite catalyst showed outstanding catalytic stability for successive recycles without appreciable loss of activity.

Electrochemical oxidation of amoxicillin on carbon nanotubes and carbon nanotube supported metal modified electrodes

Ferreira, Marta,Kuzniarska-Biernacka, Iwona,Fonseca, António M.,Neves, Isabel C.,Soares, Olívia S.G.P.,Pereira, Manuel F.R.,Figueiredo, José L.,Parpot, Pier

, p. 322 - 331 (2019/07/10)

The electrolysis of amoxicillin (AMX) was carried out on CNT, Pt/CNT and Ru/CNT modified electrodes based on Carbon Toray in 0.1 M NaOH, 0.1 M NaCl and 0.1 M Na2CO3/NaHCO3 buffer (pH 10) media with the aim of studying the significance of two factors, electrode material and pH, on the oxidative degradation and mineralization of AMX. For this purpose, the electrolysis products were identified by HPLC-MS and GC–MS, and quantified by HPLC-UV-RID and IC. The highest carbon mineralization efficiency, corresponding to 30% of the oxidized AMX, was found for Pt/CNT modified electrode in carbonate buffer medium. Regarding to the AMX conversion, the results show that the effect of pH is higher than that of the electrode material. Principal component analysis allowed to determine the experimental parameters vs. product distribution relationship and to elucidate the oxidation pathways for the studied electrodes. The results show that the hydroxylation of the aromatic ring and the nitrogen atom play an important role on the efficient degradation of AMX.

Synthesis of arylglyoxylic acids and their collision-induced dissociation

Wadhwa, Kuldeep,Yang, Chengxi,West, Paul R.,Deming, Kris C.,Chemburkar, Sanjay R.,Reddy, Rajarathnam E.

experimental part, p. 4434 - 4444 (2009/04/05)

A variety of substituted arylglyoxylic acids (2a-g) were synthesized via oxidation of the corresponding aryl-methylketones (1a-e) using selenium dioxide or Friedel-Crafts acylation of phenol (3) with ethyl chlorooxoacetate and further transformations. It was found that the arylglyoxylic acids (2) undergo facile unimolecular dissociation with loss of carbon monoxide to give the corresponding arylcarboxylic acids (7) under collisionally induced mass spectrometric conditions. Copyright Taylor & Francis Group, LLC.

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