15978-91-3

Basic information

• Product Name: dibromoplatinum(2+) diazanide
• CAS NO: 15978-91-3
• Molecular Formula: Br₂H₆N₂Pt
• Molecular Weight: 386.9372
• Mol File: 15978-91-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: dibromoplatinum(2+) diazanide(CAS DataBase Reference)
• NIST Chemistry Reference: dibromoplatinum(2+) diazanide(15978-91-3)
• EPA Substance Registry System: dibromoplatinum(2+) diazanide(15978-91-3)

Safety Data

• Hazardous Substances Data: 15978-91-3(Hazardous Substances Data)

Usage

Description

Dibromoplatinum(2+) diazanide, also known as platinum diazide dibromide, is a chemical compound characterized by a platinum (2+) cation bonded to two bromine anions and two diazanide ligands. It is recognized for its unique chemistry and reactivity, which positions it as a significant intermediate in the development of new chemical processes and materials with potential applications across various fields.

Uses

Used in Coordination Chemistry:
Dibromoplatinum(2+) diazanide serves as a precursor in the synthesis of other platinum-containing compounds and materials, playing a crucial role in the advancement of coordination chemistry. Its ability to form stable complexes with various ligands makes it a valuable component in the creation of new coordination compounds with tailored properties.
Used in Materials Science:
In the field of materials science, dibromoplatinum(2+) diazanide is utilized as a building block for the production of innovative platinum-based materials. Its incorporation into these materials can enhance their performance, leading to improved applications in various industries.
Used in Catalysis:
Dibromoplatinum(2+) diazanide has potential applications in catalysis, where it can act as a catalyst or a catalyst precursor. Its unique reactivity allows it to facilitate chemical reactions, improving efficiency and selectivity in various catalytic processes.
Used in Pharmaceutical Industry:
Dibromoplatinum(2+) diazanide is also considered for use in the pharmaceutical industry, where it may contribute to the development of new drugs or drug delivery systems. Its chemical properties could be harnessed to create novel therapeutic agents or improve the efficacy of existing treatments.
Overall, dibromoplatinum(2+) diazanide is a versatile chemical intermediate with a wide range of potential applications across different industries, including coordination chemistry, materials science, catalysis, and pharmaceuticals. Its unique chemistry and reactivity make it an important component in the development of new chemical processes and materials with promising industrial and scientific applications.

Upstream product

• 7558-02-3 potassium bromide 
• 90670-30-7 cis-diamminebis(dimethyl sulfide)platinum(II) perchlorate 
• 41349-15-9 cis-diammineoxalatoplatinum(II) 
• 10035-10-6 hydrogen bromide 
• 16893-25-7 {Pt(2)Br2} 
• 63700-88-9 cisplatin 
• 15663-27-1 cisplatin 
• 41575-87-5 cis-diaminedinitroplatinum(II) 
• 21169-98-2 {Pt(HC2O4)2} 
• 12234-22-9 {PtBr4}*{PtBr2} 
• 41575-87-5 trans-dinitrato-diammine-platinum(II) 
• 26035-31-4 transplatin 

Downstream Products

• 110790-63-1 tetraphenylphosphonium amminetribromoplatinate(II) 
• 7664-41-7 ammonia 
• 7440-06-4 platinum 
• 13455-12-4 platinum(II) bromde 
• 20115-65-5 {Pt}(2+) = trans-diaqua-diammine-platinum(II) (2+) = trans-Diaquo-diammin-platin(II) (2+) 

Relevant articles and documents

Cisplatin and its dibromido analogue: a comparison of chemical and biological profiles

The dibromido analogue of cisplatin, cis-PtBr2(NH3)2 (cisPtBr2 hereafter), has been prepared and characterised. Its solution behaviour in standard phosphate buffer, at pH 7.4, was investigated spectrophotometrically and found to reproduce quite closely that of cisplatin; indeed, progressive sequential release of the two halide ligands typically occurs as in the case of cisplatin, with a roughly similar kinetics. Afterward, patterns of reactivity toward model proteins and standard ctDNA were explored and the nature of the resulting interactions elucidated. The antiproliferative properties were then evaluated in four representative cancer cell lines, namely A549 (human lung cancer), HCT116 (human colon cancer), IGROV-1 (human ovarian cancer) and FLG 29.1 (human acute myeloid leukaemia). Cytotoxic properties in line with those of cisplatin were highlighted. From these studies an overall chemical and biological profile emerges for cisPtBr2 closely matching that of cisplatin; the few slight, but meaningful differences that were underscored might be advantageously exploited for clinical application.

Cationic binuclear platinum(II) complexes with bromide bridges

Binuclear platinum(II) complexes with bromide bridges were prepared by a reaction between platinum(II) diammine compounds.

Reactivity of cis-diamminebis (dimethyl sulfide) platinum (II) perchlorate

-