41575-87-5

Basic information

• Product Name: diamminebis(nitrato-O)platinum
• Synonyms: diamminebis(nitrato-O)platinum;cis-Diamminedinitratoplatinum(ii);Dinitratodiamminoplatinum(ii);Einecs 255-445-5;Platinum (ii), diamminedinitrato-, cis-;Platinum (ii), dinitrodiammine;Platinum, diamminebis(nitrato-kappao)-, (sp-4-2)-;cis-Diamminedinitratoplatinum
• CAS NO: 41575-87-5
• Molecular Formula: H₆N₄O₆Pt
• Molecular Weight: 351.13296
• EINECS: 255-445-5
• Product Categories: Aliphatics;Amines;Intermediates & Fine Chemicals;Pharmaceuticals;Aliphatics, Amines, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 41575-87-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 83°Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 49.8mmHg at 25°C
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMF (Slightly), Water (Slightly, Sonicated)
• CAS DataBase Reference: diamminebis(nitrato-O)platinum(CAS DataBase Reference)
• NIST Chemistry Reference: diamminebis(nitrato-O)platinum(41575-87-5)
• EPA Substance Registry System: diamminebis(nitrato-O)platinum(41575-87-5)

Safety Data

• Hazardous Substances Data: 41575-87-5(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

Different sources of media describe the Uses of 41575-87-5 differently. You can refer to the following data:
1. Synthesis and cytotoxic activity of platinum complex immobilized by branched polyethylene glycol. Platinum diammine complexes are anticancer agents for brain tumors.
2. Synthesis and cytotoxic activity of platinum complex immobilized by branched polyethylene glycol. Platinum diammine complexes are anticancer agents for brain tumors

InChI:InChI=1/2NO3.2H3N.Pt/c2*2-1(3)4;;;/h;;2*1H3;/q2*-1;;;+2

Upstream product

• 15663-27-1 cisplatin 
• 26035-31-4 transplatin 
• 15978-93-5 trans-diiododiammineplatinum(II) 
• 7697-37-2 nitric acid 
• 13841-96-8 cis-diamminediiodoplatinum (II) 

Downstream Products

• 95734-82-0 nedaplatin 
• 15663-27-1 cisplatin 
• 16893-05-3 trans-diamminetetrachloroplatinum(IV) 
• 28124-55-2 cis-diamminedithiocyanatoplatinum(II) 
• 41349-15-9 cis-diammineoxalatoplatinum(II) 
• 16893-05-3 cis-diaammineplatinum(IV) tetrachloride 
• 7440-06-4 platinum 
• 26035-31-4 transplatin 
• 15978-91-3 trans-diammine-dibromo-platinum(II) 
• 13601-52-0 cis-diamminedibromoplatinum(II) 

Relevant articles and documents

Combating metastasis of breast cancer cells with a carboplatin analogue containing an all-trans retinoic acid ligand

Pt-ATRA, a carboplatin analogue containing an all-trans retinoic acid (ATRA) derivative ligand, was synthesized via a click reaction. Upon cellular internalization, Pt-ATRA exhibits a dual function, releasing an active Pt(ii) moiety to induce cell apoptosis and ATRA to inhibit tumor metastasis.

CARRIER THAT TARGETS FUCOSYLATED MOLECULE-PRODUCING CELLS

The present invention relates to a carrier that is targeted at fucosylated molecule-producing cells, which comprises an effective amount of fucose for targeting said cells, to a composition comprising the carrier, and to a method for treating and diagnosing a disease related to fucosylated molecule-producing cells utilizing said carrier, etc. The carrier of the present invention enables to deliver a substance specifically to fucosylated molecule-producing cells.

PARTUCULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS

Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo environments.