16619-51-5

Basic information

• Product Name: 2-Propen-1-one, 3-phenyl-1-[2-(2-propenyloxy)phenyl]-
• CAS NO: 16619-51-5
• Molecular Formula: C18H16O2
• Molecular Weight: 264.324
• Mol File: 16619-51-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-phenyl-1-[2-(2-propenyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-phenyl-1-[2-(2-propenyloxy)phenyl]-(16619-51-5)
• EPA Substance Registry System: 2-Propen-1-one, 3-phenyl-1-[2-(2-propenyloxy)phenyl]-(16619-51-5)

Safety Data

• Hazardous Substances Data: 16619-51-5(Hazardous Substances Data)

Upstream product

• 644-78-0 2-hydroxychalcone 
• 106-95-6 allyl bromide 
• 100-52-7 benzaldehyde 
• 118-93-4 o-hydroxyacetophenone 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 53327-14-3 2'-allyloxyacetophenone 

Downstream Products

• 1657006-73-9 C₁₈H₁₆Br₂O₂ 
• 525-82-6 FLAVONE 
• 178666-52-9 (E)-1-(3-Allyl-2-hydroxy-phenyl)-3-phenyl-propenone 
• 34183-22-7 propafenone hydrochloride 
• 22525-95-7 1-(2-(oxiran-2-ylmethoxy)phenyl)-3-phenylpropan-1-one 
• 98153-12-9 3-iodo-2-phenyl-4H-1-benzopyran-4-one 
• 141522-38-5 (10S,15R)-15-Phenyl-8-oxa-12,13-dithia-tricyclo[8.3.2.0^2,7]pentadeca-1⁽¹⁴⁾,2,4,6-tetraene 
• 141522-41-0 3-Phenyl-10,10a-dihydro-1H,4aH-9-oxa-2-thia-phenanthrene 

Relevant articles and documents

Visible Light Promoted Chan-Lam Reaction and Cycloaddition to Prepare Chromeno[4,3-c]isoxazolidines in One-Pot Reaction

A variety of chromeno[4,3-c]isoxazolidines were prepared in good yields through visible light promoted Chan-Lam reaction and [3+2] cycloaddition cascade reaction in one pot. Mechanistic studies showed that visible light promoted both Chan-Lam reaction and cycloaddition. The obtained products were converted to various useful chromenone derivatives. Moreover, the reaction was easily performed at gram scales with the purification of products without column chromatography and used to efficiently synthesize estrone-derived chromeno[4,3-c]isoxazolidine. (Figure presented.).

Iodine-mediated direct synthesis of 3-iodoflavones

Molecular iodine has been used for the regioselective, one pot, direct synthesis of 3-iodoflavones from 2′-allyloxy chalcones, 2′-hydroxy chalcones and flavones. Allyl deprotection, cyclization dehydrogenation and α-iodination of 2′-allyloxychalcones has been achieved in a single step to offer 3-iodoflavones.

Sodium-iodoxybenzoate mediated highly chemoselective aziridination of olefins

Herein we utilized, for the first time, sodium 2-iodoxybenzoate as a highly specific oxidant for PhthNH2 to create a highly chemoselective aziridination reagent. This method efficiently effects aziridination of electron-rich, electron-deficient, allylic alcohol and alkenyl bromide C=C bonds in good to excellent yields. Inter and intramolecular chemoselectivity was demonstrated between electron-rich and electron-deficient alkenes by using this efficient and metal free protocol.