19493-09-5Relevant articles and documents
Efficient Synthesis of (+/-)-Solavetivone and (+/-)-2H2>Solavetivone
Murai, Akio,Sato, Shingo,Masamune, Tadashi
, p. 2282 - 2285 (1984)
An alternative and efficient synthesis of the title compounds is described.The synthesis involves cycloaddition of 2-methylene-4-methoxy-6-methyl-4-cyclohexenylacetonitrile with methyl vinyl ketone as a key step.
Synthesis based on cyclohexadienes. Part 34. A tandem cationic rearrangement-ene cyclisation route to 2-pupukeanone
Biju, P. John,Kaliappan, Krishna,Laxmisha,Subba Rao
, p. 3714 - 3718 (2000)
A tandom cationic rearrangement-ene cyclisation route to 2-pupukeanone was discussed. The synthesis of 2-pupukeanone was done using a one-pot tandom acid-catalysed rearrangement. Results showed that 2-pupukeanone could be obtained from the tricyclic keton
Ring-closing metathesis as a key step to construct the 2, 6-dihydropyrano[2, 3-c]pyrazole ring system
Bieliauskas, Aurimas,Krik?tolaityte, Sonata,Holzer, Wolfgang,?ackus, Algirdas
, p. 296 - 307 (2018)
A simple and efficient synthetic route to the 2, 6-dihydropyrano[2, 3-c]pyrazole ring system was developed by employing ring-closing metathesis (RCM) as a key step. The required diene substrate for the RCM reaction was prepared by a three-step procedure s
Synthesis of A-Ring Precursors of 1α,25-Dihydroxyvitamin D3 Analogues Functionalized at C-2
Sigüeiro, Rita
, p. 6797 - 6803 (2017)
A flexible approach to an A-ring building block for new 1α,25-dihydroxyvitamin D analogues functionalized at C-2 as potential clinical candidates is described. The synthesis of alcohol 5 starts from (R)-carvone, and uses a Criegee rearrangement to selecti
"Umgepolte" 1.3-diaza-fulvene
Gompper, Rudolf,Bichlmayer, Klaus Peter
, p. 2879 - 2882 (1980)
6-Subtituted 2.4-diamino-1.3-diazafulvenes with inverse fulvene polarity are readily available from 2.4.5.-tris-(diethylamino)-4-ethoxy-4H-imidazole and active methylene compounds.
Synthesis and photodynamic properties of pyrazole-indole hybrids in the human skin melanoma cell line G361
?a?kus, Algirdas,?ukauskait?, Asta,Bieliauskas, Aurimas,Ho?íková, Barbora,Kleizien?, Neringa,Kolá?ová, Hana,Kry?tof, Vladimír,Malina, Luká?,Simerská, Helena,Varvuolyt?, Gabriel?
, (2020)
Three conjugated pyrazole-indole hybrids, 5, 7 and 10, were synthesized from easily accessible 3-(hexyloxy)-1-phenyl-1H-pyrazole-4-carbaldehyde 1 and 5-iodo-3,3-dimethyl-2-phenyl-3H-indole 4 employing olefination reactions (Wittig, Ramirez), Vilsmeier-Haa
Synthesis of 4-(1,5,9-Trimethyl-1-vinyl-4,8-decadienyl)catechol Dimethyl Ether
Anand, Ramesh Chander,Ranjan, Harish
, p. 791 - 792 (1985)
Synthesis of 4-(1,5,9-trimethyl-1-vinyl-4,8-decadienyl)catechol dimethyl ether has been described utilizing Wittig reaction for the introduction of vinylic substituent at the quaternary carbon.
Total synthesis of amphilectane-type diterpenoid (±)-7- isocyanoamphilecta-11(20),15-diene
Miyaoka, Hiroaki,Okubo, Yusuke
, p. 547 - 550 (2011)
The total synthesis of amphilectane-type diterpenoid (±)-7- isocyanoamphilecta-11(20),15-diene, isolated from the tropical marine sponge Cymbastela hooperi, was achieved. The synthesis involves construction of a cis-decalin ring by an intramolecular Diels-Alder reaction and construction of an all-trans-perhydrophenalene ring by an intramolecular Michael reaction as the key steps. Georg Thieme Verlag Stuttgart.
Modifying the chemistry of the phosphole dienic system by α-vinylation
Ng, Kim Hong,Li, Yongxin,Ganguly, Rakesh,Mathey, Francois
, p. 4245 - 4250 (2014)
1-Phenyl-2-vinyl-3,4-dimethylphosphole (4) was prepared from the corresponding 2-carboxaldehyde via a Wittig reaction. The reaction of its P-W(CO)5 complex 5 with [PhP-W(CO)5] selectively takes place at the vinyl double bond and give
Asymmetric synthesis and absolute stereochemistry of a labdane-type diterpenoid isolated from the rhizomes of: Isodan yuennanensis
Deng, Heping,Cao, Wei,Zhang, Zhijiang,Liu, Bo
, p. 6225 - 6230 (2016)
The first synthesis of a labdane-type diterpenoid isolated from Isodon yuennanensis was achieved in fourteen steps from commercially available starting material, (+)-sclareolide. The synthesis features the Barton nitrite ester reaction to introduce an oxi