20515-61-1Relevant articles and documents
Synthesis of dioxolanes and oxazolidines by silica gel catalysis
Rohand, Taoufik,Savary, Jér?me,Markó, István E.
, p. 1429 - 1436 (2018/06/25)
Abstract: Ethylene glycol condensed with carbonyl compounds in the presence of silica gel or alumina, without solvent and under pressure, affords 1,3-dioxolanes. 2-Amino-2-methylpropanol also condensed with carbonyl compounds in the presence of silica gel or an acid-activated clay, without solvent and under pressure, produces oxazolidines. To explain these results, we propose that the glycol and the aminopropanol react with Br?nsted (H+) and Lewis acid sites (Si and Al) located on the surface of the catalysts, leading to the products via various ionic intermediates.
Efficient oxidative synthesis of 2-oxazolines
Schwekendiek, Kirsten,Glorius, Frank
, p. 2996 - 3002 (2008/02/10)
New methodology for the synthesis of variously substituted 2-oxazolines and one dihydrooxazine using aldehydes, amino alcohols, and N-bromosuccinimide as an oxidizing agent is described. This one-pot synthesis is characterized by mild reaction conditions, broad scope, high yields, and its preparative simplicity. Georg Thieme Verlag Stuttgart.
HYDROXY SCHIFF BASE-OXAZOLIDINE TAUTOMERISM: APPARENT BREAKDOWN OF BALDWIN'S RULES
Astudillo, Mario E. Alva,Chokotho, Norris C. J.,Jarvis, Terence C.,Johnson, C. David,Lewis, Colin C.,McDonnell, Peter D.
, p. 5919 - 5928 (2007/10/02)
The tautomerism between hydroxy Schiff bases, X=C6H4CR=NCMe2CH2OH (R=H, Me, C6H5; X is a range of substituents) and X=C6H4CR=NC6H4(o-CH2OH), and the corresponding ring closed systems, oxazolidines and dihydrobenzoxazines, has been investigated.In all case