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2-methyl-2-[(E)-phenylmethylidene]aminopropan-1-ol, also known as phenylmethylideneamine or 2-methylpropan-1-ol, is a chemical compound characterized by the molecular formula C10H15NO. It is a clear, colorless liquid with a faint odor, and it plays a significant role in various industrial applications due to its versatile chemical properties.

22563-90-2

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22563-90-2 Usage

Uses

Used in Pharmaceutical Industry:
2-methyl-2-[(E)-phenylmethylidene]aminopropan-1-ol is utilized as an important intermediate in the synthesis of various pharmaceutical drugs and organic compounds. Its unique structure allows it to be a key component in the development of new medications, contributing to advancements in healthcare.
Used in Chemical Industry:
In the chemical industry, 2-methyl-2-[(E)-phenylmethylidene]aminopropan-1-ol is employed as a solvent in the production of perfumes, dyes, and resins. Its solvent properties make it suitable for dissolving a wide range of substances, facilitating various chemical processes and product formulations.
Used in Plastics and Rubber Industry:
2-methyl-2-[(E)-phenylmethylidene]aminopropan-1-ol is used in the production of antioxidants and stabilizers for plastics and rubber. Its application helps to enhance the durability and performance of these materials, ensuring their longevity and resistance to degradation under various conditions.
Overall, 2-methyl-2-[(E)-phenylmethylidene]aminopropan-1-ol is a versatile chemical compound with a wide range of industrial applications, from pharmaceuticals to the production of everyday materials. Its diverse uses underscore its importance in modern industry.

Check Digit Verification of cas no

The CAS Registry Mumber 22563-90-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,6 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22563-90:
(7*2)+(6*2)+(5*5)+(4*6)+(3*3)+(2*9)+(1*0)=102
102 % 10 = 2
So 22563-90-2 is a valid CAS Registry Number.

22563-90-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(benzylideneamino)-2-methylpropan-1-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22563-90-2 SDS

22563-90-2Relevant articles and documents

Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols

de Almeida, Camila G.,Reis, Samira G.,de Almeida, Angelina M.,Diniz, Claudio G.,da Silva, Vania L.,Le Hyaric, Mireille

experimental part, p. 876 - 880 (2012/06/18)

Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus epidermidis (minimal inhibitory concentrations = 32μm).

AMIDOPYRAZOLE DERIVATIVE

-

Page/Page column 83-84, (2010/11/23)

A platelet coagulation inhibitor which inhibits neither COX-1 nor COX-2 is provided. The inhibitor is a compound represented by general formula (I): wherein Ar1 and Ar2 independently represent a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents, or a phenyl group optionally substituted with 1 to 3 substituents; R1 represents a lower acyl group, carboxyl group, a lower alkoxycarbonyl group, a lower alkoxy group, a lower alkyl group optionally substituted with 1 or 2 substituents, a carbamoyl group optionally substituted with 1 or 2 substituents, an oxamoyl group optionally substituted with 1 or 2 substituents, an amino group optionally substituted with 1 or 2 substituents, a 4- to 7-membered alicyclic heterocyclic group optionally substituted with 1 or 2 substituents, a phenyl group optionally substituted with 1 to 3 substituents, or a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents; and R2 represents hydrogen atom, a halogeno group, or the like.

Improved syntheses of fluorinated tertiary butylamines

Ok, Dong,Fisher, Michael H.,Wyvratt, Matthew J.,Meinke, Peter T.

, p. 3831 - 3834 (2007/10/03)

Two new and efficient methods using cyclic sulfamidate and nitrone chemistry were developed for the synthesis of the sterically congested 1,1- dimethyl-2-fluoroethylamine (1), 2-fluoro-1-(fluoromethyl)-1-methylethylamine (2) and 2-fluoro-1,1-bis-(fluoromethyl)-ethylamine (3).

Bicyclic and tricyclic compounds with β-amino alcohol groups as chiral ligands in the enantioselective reaction of diethylzinc with aldehydes

Aurich, Hans Guenter,Biesemeier, Frank,Geiger, Michael,Harms, Klaus

, p. 423 - 434 (2007/10/03)

Reduction of the enantiomerically pure allyloxy esters 9 or ent-9 with DIBAH afforded the corresponding aldehydes which were treated in situ with chiral or achiral hydroxylamines 8 to give nitrones 10. These underwent a spontaneous intramolecular 1,3-dipolar cycloaddition, affording the bicyclic compounds 11 and 12, respectively. In an analogous manner, a mixture of the tricyclic compounds 14 and 15 was prepared. Treatment of compound 16 with cyclohexene oxide afforded a mixture of diastereomers 17 and 18. Diastereomers 14 and 15 as well as 17 and 18 could be separated by chromatography. X-ray analyses of compounds 11Ff, 17, and 11Af · HCI were performed. The bicyclic and tricyclic compounds were used as chiral ligands in the reaction of diethylzinc with aldehydes 19, in particular with benzaldehyde (19a). Using bicyclic compounds with a tertiary β-hydroxyalkyl substituent at the N atom as ligands, ee's in the range of 78 to 95% were found. Whereas for the best ligands 11Ae and Af the enantioselectivity in the reaction of 4-tolualdehyde was only slightly decreased, with the aliphatic aldehydes 19c and d distinctly lower enantioselectivities were determined. VCH Verlagsgesellschaft mbH, 1997.

Regio- and Diastereoselectivity in the Reaction Sequence from Secondary 3-Oxa-5-hexen-1-ylamines to Bicyclic Compounds via Nitrones

Aurich, Hans Günter,Geiger, Michael,Sievers, Ulrich

, p. 1004 - 1006 (2007/10/03)

Secondary amines 2 and 8 are oxidized by hydrogen peroxide in the presence of sodium tungstate providing nitrones. It the amino function is substituted by one primary and one secondary alkyl moiety, oxidation proceeds with high regioselectivity at the primary alkyl group affording aldonitrones. Thus, compound 2b gives exclusively 3b that undergoes an intramolecular cycloaddition yielding 4b. From 2c, however, in addition to 4c nitrone 5 is formed as by-product, which affords the bridged compound 6 on heating in toluene. Oxidation of compounds 8 yields nitrones 9 which are converted to bridged compounds 10 as major products along with small amounts of regioisomers 11 at elevated temperatures. The intramolecular cycloaddition of the chiral nitrones 3b and c as well as 9b proceeds with high diastereoselectivity.

ELECTROREDUCTION OF 2-OXAZOLINES

Ryan, Christopher M.,Kariv-Miller, Essie

, p. 6807 - 6810 (2007/10/02)

The cathodic behavior of 2-phenyl-4,4-dimethyl-2-oxazoline (4), 2,4,4-trimethyl-2-oxazoline (7) and 2-(1,1-dimethylethyl)-4,4-dimethyl-2-oxazoline (8) at Hg electrodes was investigated.A reduction peak for 4 at -2.49V (SCE), was observed by cyclic voltamm

HYDROXY SCHIFF BASE-OXAZOLIDINE TAUTOMERISM: APPARENT BREAKDOWN OF BALDWIN'S RULES

Astudillo, Mario E. Alva,Chokotho, Norris C. J.,Jarvis, Terence C.,Johnson, C. David,Lewis, Colin C.,McDonnell, Peter D.

, p. 5919 - 5928 (2007/10/02)

The tautomerism between hydroxy Schiff bases, X=C6H4CR=NCMe2CH2OH (R=H, Me, C6H5; X is a range of substituents) and X=C6H4CR=NC6H4(o-CH2OH), and the corresponding ring closed systems, oxazolidines and dihydrobenzoxazines, has been investigated.In all case

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