2150-41-6

Basic information

• Product Name: METHYL 2,4-DIMETHOXYBENZOATE
• Synonyms: METHYL 2,4-DIMETHOXYBENZOATE;2,4-Dimethoxybenzoic acid methyl ester;Methyl 2,4-dimethoxybenzoate 98%;RARECHEM AL BF 0025
• CAS NO: 2150-41-6
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: C10 to C11;Carbonyl Compounds;Esters
• Mol File: 2150-41-6.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 294-296 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.194 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000921mmHg at 25°C
• Refractive Index: n20/D 1.548(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 2,4-DIMETHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2,4-DIMETHOXYBENZOATE(2150-41-6)
• EPA Substance Registry System: METHYL 2,4-DIMETHOXYBENZOATE(2150-41-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 2150-41-6(Hazardous Substances Data)

Usage

Uses

Methyl 2,4-dimethoxybenzoate was used in the synthesis of 1,5-diaryl-1,3,5-pentanetriones.

General Description

Methyl 2,4-dimethoxybenzoate has highest antifeedant index and are the best candidates for practical applications in order to protect planted seedlings in the field.

InChI:InChI=1/C10H12O4/c1-12-7-4-5-8(10(11)14-3)9(6-7)13-2/h4-6H,1-3H3

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 77-78-1 dimethyl sulfate 
• 5446-02-6 4-methoxymethylsalicylate 
• 3186-53-6 O-methyl S-p-methylphenyl thiocarbonate 
• 133730-34-4 2,4-dimethoxyphenylboronic acid 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 7438-18-8 2,4-dimethoxybenzenediazonium tetrafluoroborate 
• 616-38-6 carbonic acid dimethyl ester 
• 2150-47-2 methyl 2,4-dihydroxybenzoate 
• 108-46-3 recorcinol 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 75-91-2 tert.-butylhydroperoxide 
• 7314-44-5 2,4-dimethoxylbenzyl alcohol 

Downstream Products

• 5446-02-6 4-methoxymethylsalicylate 
• 1609699-52-6 methyl 5-((2-(5-bromopyridin-2-yl)hydrazono)methyl)-2,4-dimethoxybenzoate 
• 1609699-53-7 methyl 5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxybenzoate 
• 1609699-87-7 5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxybenzoic acid 
• 1609699-88-8 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxyphenyl)(4-methylpiperazin-1-yl)methanone 
• 1609699-89-9 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxyphenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone 
• 1609699-55-9 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl)(4-methylpiperazin-1-yl)methanone 
• 1609699-56-0 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone 
• 39503-63-4 methyl 5-formyl-2,4-dimethoxybenzoate 
• 7314-44-5 2,4-dimethoxylbenzyl alcohol 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 76832-37-6 2,4,2’,4’,2”,4”-hexamethoxytriphenylcarbinol 
• 94312-76-2 2,3-bis-(2,4-dimethoxy-phenyl)-3-oxo-propionitrile 

Relevant articles and documents

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Synthesis, Antiproliferative and Antioxidant Activity of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogues

Two series of 3-mercapto-1,2,4-triazole derivatives containing alkoxy substituents different in size and position were synthesized and their structures were characterized by FT-IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. The synthesized compounds were assessed for their antiproliferative activity against colon cancer cell line (SW480). The results indicated that the size and position of the alkoxy group significantly influenced the antiproliferative activity. The highest cancer cell growth inhibition values were observed for the compounds containing 3,4,5-trimethoxyphenyl groups in their structures (57.74, 54.14 and 60.70% at 50 μM for compounds 5a, 12b and 14, respectively). The synthesized compounds were also subjected to DPPH protocol for evaluating the antioxidant activity. The results showed that all compounds had moderate to high levels of antioxidant capacity as compared to ascorbic acid as standard, the highest free radical scavenging capacity of 75% was observed for compound 4a at 50 μM.

Synthesis of acyclic and cyclic phosphonates based on substituted 2-hydroxybenzylic alcohols

A convenient synthesis of benzylic phosphonates and 2,3-dihydrobenzo[d][1,2]oxaphosphole 2-oxides substituted at the aromatic ring, as well as their precursors, 2-hydroxybenzylic alcohols, from the derivatives of salicylic aldehyde, salicylic acid, and 2-hydroxyacetophenone bearing an additional hydroxy or methoxy group at the para position of the aromatic ring was developed. For the first time, the possibility of selective demethylation of the methoxy group positioned ortho to the methylene phosphonate fragment with retention of the methoxy group at the para position was shown.

Electrochemical C-H cyanation of electron-rich (Hetero)arenes

A straightforward method for the electrochemical C-H cyanation of arenes and heteroarenes that proceeds at room temperature in MeOH, with NaCN as the reagent in a simple, open, undivided electrochemical cell is reported. The platinum electrodes are passivated by ad-sorbed cyanide, which allows conversion of an exceptionally broad range of electron-rich substrates all the way down to dialkyl arenes. The cyanide electrolyte can be replenished with HCN, opening opportunities for salt-free industrial C-H cyanation.