27412-71-1

Basic information

• Product Name: 3-Hydroxy-5-phenyl-1H-pyrazole
• Synonyms: 1,2-Dihydro-5-phenyl-3H-pyrazol-3-one;3-Hydroxy-5-phenyl-1H-pyrazole;5-Phenyl-1H-pyrazole-3(2H)-one;5-Phenyl-1H-pyrazole-3-ol;5-Phenyl-1H-pyrazol-3(2H)-one
• CAS NO: 27412-71-1
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17
• Mol File: 27412-71-1.mol
• Article Data: 19

Chemical Properties

• Melting Point: 237 °C
• Appearance: /
• Density: 1.206±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.51±0.70(Predicted)
• CAS DataBase Reference: 3-Hydroxy-5-phenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-5-phenyl-1H-pyrazole(27412-71-1)
• EPA Substance Registry System: 3-Hydroxy-5-phenyl-1H-pyrazole(27412-71-1)

Safety Data

• Statements: 20/22
• Safety Statements: 36/37
• Hazardous Substances Data: 27412-71-1(Hazardous Substances Data)

Upstream product

• 3446-58-0 3-oxo-3-phenylpropanamide 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 109592-72-5 3-phenyl-3-(1⁽²⁾H-pyrazole-3-carbonylhydrazono)-propionic acid ethyl ester 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 7803-57-8 hydrazine hydrate 
• 959-66-0 3-oxo-3-phenylpropionanilide 
• 870-46-2 t-butoxycarbonylhydrazine 
• 16105-56-9 3-ethoxy-5-phenyl-1H-pyrazole 
• 1207432-08-3 ethyl 3-ethoxy-5-phenyl-1H-pyrazole-4-carboxylate 
• 16439-95-5 4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 98-88-4 benzoyl chloride 
• 1081820-31-6 ethyl 2-benzoyl-3-hydroxy-2-butenoate 
• 64-17-5 ethanol 
• 116519-41-6 ethyl β-ethoxycinnamate 

Downstream Products

• 79994-66-4 3-phenyl-1,2,4-trimethylpyrazolin-3-one 
• 13572-29-7 3-phenyl-4-phenylhydrazono-2-pyrazolin-5-one 
• 66076-96-8 (3-oxo-5-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-(5-oxo-3-phenyl-1,5-dihydro-pyrazol-4-ylidene)-methane 
• 32258-59-6 acetic acid-(5-phenyl-1⁽²⁾H-pyrazol-3-yl ester) 
• 39513-07-0 3-methoxy-5-phenyl-1⁽²⁾H-pyrazole 
• 80030-92-8 2-methyl-5-phenyl-2,3-dihydro-1H-pyrazol-3-one 
• 138023-92-4 4-(4-diethylamino-phenylimino)-5-phenyl-2,4-dihydro-pyrazol-3-one 
• 486-38-4 1,2-dimethyl-5-phenyl-1,2-dihydro-pyrazol-3-one 
• 66076-87-7 4,4-dibromo-3-phenyl-2-pyrazolin-5-one 
• 1688-32-0 4-oximino-3-phenyl-2-pyrazolin-5-one 

Relevant articles and documents

Synthesis and studies of a tetradecanuclear manganese(II)/(III) cage

A novel Mn14 cluster is reported; this is a new nuclearity for manganese cages and highly unusual in that the ligands are not exclusively oxygen donors.

Hydrohydrazination of Arylalkynes Catalyzed by an Expanded Ring N-Heterocyclic Carbene (er-NHC) Gold Complex under Solvent-Free Conditions

[(THD-Dipp)AuOTf], supported by the strongly electron donating, sterically bulky THD-Dipp (1,3-bis(2,6-diisopropylphenyl)hexahydro-2H-1,3-diazepine-2-ylidene) seven-membered N-heterocyclic carbene ligand, efficiently promotes intermolecular addition of Ts- and Boc-hydrazine to arylalkynes under solvent-free conditions.

Exploration of isosteric replacement of imidazolidinone motif in 4-phenyl-1-arylsul-fonylimidazolidinone with pyrazole and pyrazolidinone for cytotoxicity

To investigate the possible isosteric replacement of imidazolidinone moiety in 4-phenyl-1-arylsulfonyl-imidazolidinones (2) for broad and potent anti-cancer agents, a series of 5-phenyl-1H-pyrazol-3-yl 1-(acyl)indoline-5-sulfonates (4) and 1-(1-(acyl)indo