486-38-4 Usage
Chemical structure
1,2-Dihydro-1,2-dimethyl-5-phenyl-3H-pyrazol-3-one
Class
Pyrazolone derivatives
Appearance
Unknown, but likely a solid due to its molecular weight and structure
Solubility
Unknown, but likely soluble in organic solvents such as ethanol or methanol
Pharmacological properties
Antidepressant activity due to inhibition of serotonin reuptake
Discontinued
Yes, due to concerns about causing Guillain-Barré syndrome
Current status
Primarily of interest to researchers studying chemical structures and pharmacological properties of pyrazolone derivatives
Potential applications
Research and development in the field of medicinal chemistry and drug discovery
Safety concerns
Guillain-Barré syndrome risk
Mechanism of action
Inhibition of serotonin reuptake in the brain, leading to increased levels of serotonin and improved mood regulation
Chemical properties
Unknown, but likely stable under normal conditions due to its structure
Synthesis
Unknown, but likely synthesized through chemical reactions involving pyrazolone and phenyl groups
Structural features
Pyrazolone ring, phenyl group, and two methyl groups attached to the 1,2-positions of the pyrazolone ring
Check Digit Verification of cas no
The CAS Registry Mumber 486-38-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 486-38:
(5*4)+(4*8)+(3*6)+(2*3)+(1*8)=84
84 % 10 = 4
So 486-38-4 is a valid CAS Registry Number.
486-38-4Relevant articles and documents
HETEROCYCLIC COMPOUND AS PROTEIN KINASE INHIBITOR
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Page/Page column 38, (2011/08/06)
Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.
A new method for synthesis of 1H-pyrazol-3(2H)-ones
Magedov,Smushkevich
, p. 845 - 848 (2007/10/02)
A new preparative method is reported for the synthesis of 4,5-disubstituted 1,2-dimethyl-1H-pyrazol-3(2H)-ones 5a-e,g-k from N,N-diacyl-N,N'-dimethylhydrazines 1a-e,g,h,j,k. The method is based on the intramolecular formation of thc 4,5-bond in the pyrazo
