29809-14-1

Basic information

• Product Name: 1,2,3,4-tetrahydro-5-nitronaphthalene
• Synonyms: 1,2,3,4-tetrahydro-5-nitronaphthalene;Naphthalene, 1,2,3,4-tetrahydro-5-nitro-;5-Nitrotetralin
• CAS NO: 29809-14-1
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.19984
• EINECS: 249-864-2
• Mol File: 29809-14-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 295.3°Cat760mmHg
• Flash Point: 136.5°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 0.00271mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1,2,3,4-tetrahydro-5-nitronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-tetrahydro-5-nitronaphthalene(29809-14-1)
• EPA Substance Registry System: 1,2,3,4-tetrahydro-5-nitronaphthalene(29809-14-1)

Safety Data

• Hazardous Substances Data: 29809-14-1(Hazardous Substances Data)

Usage

General Description

1,2,3,4-tetrahydro-5-nitronaphthalene is a chemical compound that consists of a naphthalene ring with a nitro group attached to the 5th carbon atom and four hydrogen atoms attached to the remaining carbon atoms. It is a yellow crystalline solid with a molecular formula of C10H11NO2. 1,2,3,4-tetrahydro-5-nitronaphthalene is primarily used as an intermediate in the synthesis of other organic compounds and is not widely used for commercial purposes. It is important to handle 1,2,3,4-tetrahydro-5-nitronaphthalene with care, as it is considered to be a hazardous chemical and can be harmful if ingested or inhaled.

InChI:InChI=1/C10H11NO2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7H,1-2,4,6H2

Upstream product

• 119-64-2 tetralin 
• 90-15-3 α-naphthol 
• 7664-93-9 sulfuric acid 

Downstream Products

• 603-11-2 3-nitrophthalic acid 
• 112534-15-3 (2-carboxy-6-nitro-phenyl)-glyoxylic acid 
• 112534-27-7 (2-carboxy-3-nitro-phenyl)-glyoxylic acid 
• 40153-45-5 N-(4-nitro-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 
• 19356-99-1 N-(5,6,7,8-tetrahydro-[1]naphthyl)-phthalamic acid 
• 41823-28-3 5-amino-3,4-dihydronaphthalen-1(2H)-one 
• 826-67-5 1,3,4,5-tetrahydrobenz[c,d]indole 
• 57536-84-2 1-(5-tetralinyl)piperazine 
• 58161-31-2 8-nitro-3,4-dihydro-1(2H)naphthalenone 
• 51114-73-9 5-nitro-1-tetralone 
• 86-57-7 1-Nitronaphthalene 
• 2217-41-6 1-amino-5,6,7,8-tetrahydronaphthalene 
• 2217-43-8 6-amino-1,2,3,4-tetrahydronaphthalene 

Relevant articles and documents

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

Conformationally constrained analogues of N′-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists

A series of bicyclic analogues having indan and tetrahydronaphthalene templates in the A-region were designed as conformationally constrained analogues of our previously reported potent TRPV1 antagonists (1, 3). The activities for rat TRPV1 of the conformationally restricted analogues were moderately or markedly diminished, particularly in the case of the tetrahydronaphthalene analogues. The analysis indicated that steric constraints at the benzylic position in the bicyclic analogues may be an important factor for their unfavorable interaction with the receptor.