35292-56-9

Basic information

• Product Name: Hydrazine, 1-(1-methylethyl)-1-phenyl-
• CAS NO: 35292-56-9
• Molecular Formula: C9H14N2
• Molecular Weight: 150.224
• Mol File: 35292-56-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Hydrazine, 1-(1-methylethyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1-(1-methylethyl)-1-phenyl-(35292-56-9)
• EPA Substance Registry System: Hydrazine, 1-(1-methylethyl)-1-phenyl-(35292-56-9)

Safety Data

• Hazardous Substances Data: 35292-56-9(Hazardous Substances Data)

Upstream product

• 42116-43-8 tert-butyl 2-phenylhydrazine-1-carboxylate 
• 100-63-0 phenylhydrazine 
• 768-52-5 N-Isopropylaniline 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 3314-35-0 3-Amino-1-phenyl-2-pyrazoline 
• 75-26-3 isopropyl bromide 
• 75-30-9 2-iodo-propane 
• 106087-11-0 3-Amino-1-isopropyl-1-phenyl-4,5-dihydro-1H-pyrazol-1-ium; iodide 
• 24642-83-9 N-isopropyl-N-phenylnitrous amide 
• 885669-11-4 acetic acid-(N'-isopropyl-N'-phenyl-hydrazide) 

Downstream Products

• 77612-45-4 1-Isopropyl-1-phenyl-2-(3-sulfamoyl-4-chlorobenzoyl)-hydrazine 
• 1416897-72-7 (E)-methyl 3-(2-(isopropylamino)phenyl)acrylate 
• 117788-16-6 1-isopropyl-2,3-diphenyl-1H-indole 
• 76051-12-2 methyl 2-(isopropylphenylhydrazono)-4-phenyl-4-oxobutyrate 
• 136119-34-1 (Z)-1-(N'-Isopropyl-N'-phenyl-hydrazino)-5-methyl-hex-1-en-3-one 
• 136119-34-1 (E)-1-(N'-Isopropyl-N'-phenyl-hydrazino)-5-methyl-hex-1-en-3-one 
• 99380-56-0 (E)-2-Ethyl-3-(N'-isopropyl-N'-phenyl-hydrazino)-but-2-enenitrile 
• 25221-05-0 Benzophenon-N-isopropyl-N-phenylhydrazon 
• 885669-11-4 acetic acid-(N'-isopropyl-N'-phenyl-hydrazide) 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

MEDICINAL COMPOSITION

The present invention is composed of a pharmaceutical composition for the therapy of nephritis which comprises an amide derivative represented by the following formula [1] or pharmaceutically acceptable salt thereof, as an active ingredient: ???wherein R1 and R2 may be the same or different and each is hydrogen, alkyl which may be substituted, acyl, aryl which may be substituted, or an aromatic heterocyclic group which may be substituted; R3, R4, R5 and R6 may be the same or different and each is hydrogen, halogen, hydroxy, amino which may be substituted, alkyl which may be substituted, alkoxy or nitro and the like; and R7 represents cyclic amino which may be substituted or azabicycloalkylamino which may be substituted. The pharmaceutical composition of the invention is useful for the therapy of nephritis.

AMIDRAZONES 9. CONVENIENT SYNTHESIS OF 1-ALKYL-1-PHENYLHYDRAZINES AND α,β-UNSATURATED AMIDRAZONES VIA BASE-PROMOTED REACTIONS OF 1,1-DISUBSTITUTED-3-AMNIO-4,5-DIHYDRO-1H-PYRAZOLIUM SALTS.

A simple, efficient procedure for the conversion of phenylhydrazine to 1-alkyl-1-phenylhydrazines via base-promoted hydrolysis of 1-alkyl-3-amino-4,5-dihydro-1-phenyl-1H-pyrazolium iodides (2) is described.N',N'-disubstituted hydrazones of trans-cinnamamide and acrylamide are obtained by Hofmann-type ring openings of 1,1-disubstituted-3-amino-4,5-dihydro-5-phenyl (or 5-unsubstituted) -1H-pyrazolium halides (5,7).