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3678-72-6

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3678-72-6 Usage

Description

4-DIPHENYLMETHYLPYRIDINE, also known as DPHMP, is a pyridine derivative with the molecular formula C20H17N. It is characterized by a diphenylmethyl group attached to the pyridine ring, resulting in a white to off-white crystalline powder. DPHMP is insoluble in water but readily soluble in organic solvents. This chemical compound is widely recognized for its applications in organic synthesis as a ligand and in the production of pharmaceuticals and agrochemicals. Moreover, it has garnered interest for its potential medicinal uses, such as an anti-inflammatory and antioxidant agent.

Uses

Used in Organic Synthesis:
4-DIPHENYLMETHYLPYRIDINE is used as a ligand in organic synthesis for its ability to facilitate various chemical reactions, enhancing the efficiency and selectivity of the processes involved.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 4-DIPHENYLMETHYLPYRIDINE is utilized as an intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Production:
Similarly, in agrochemicals, 4-DIPHENYLMETHYLPYRIDINE serves as an intermediate, playing a crucial role in the creation of substances that protect crops from pests and diseases.
Used in Medicinal Applications:
4-DIPHENYLMETHYLPYRIDINE is studied for its potential as an anti-inflammatory agent, which could be beneficial in treating conditions characterized by inflammation.
4-DIPHENYLMETHYLPYRIDINE is also considered for its antioxidant properties, which may help in protecting cells from damage caused by reactive oxygen species and thus have implications in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 3678-72-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,7 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3678-72:
(6*3)+(5*6)+(4*7)+(3*8)+(2*7)+(1*2)=116
116 % 10 = 6
So 3678-72-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H15N/c1-3-7-15(8-4-1)18(16-9-5-2-6-10-16)17-11-13-19-14-12-17/h1-14,18H

3678-72-6 Well-known Company Product Price

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  • Aldrich

  • (D213209)  Diphenyl-4-pyridylmethane  99%

  • 3678-72-6

  • D213209-10G

  • 1,599.39CNY

  • Detail

3678-72-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-benzhydrylpyridine

1.2 Other means of identification

Product number -
Other names diphenyl-pyridin-4-ylmethane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3678-72-6 SDS

3678-72-6Relevant articles and documents

Metal-Free Heterogeneous Semiconductor for Visible-Light Photocatalytic Decarboxylation of Carboxylic Acids

Shi, Jiale,Yuan, Tao,Zheng, Meifang,Wang, Xinchen

, p. 3040 - 3047 (2021/03/09)

A suitable protocol for the photocatalytic decarboxylation of carboxylic acids was developed with metal-free ceramic boron carbon nitrides (BCN). With visible light irradiation, BCN oxidize carboxylic acids to give carbon-centered radicals, which were trapped by hydrogen atom donors or employed in the construction of the carbon-carbon bond. In this system, both (hetero)aromatic and aliphatic acids proceed the decarboxylation smoothly, and C-H, C-D, and C-C bonds are formed in moderate to high yields (35 examples, yield up to 93%). Control experiments support a radical process, and isotopic experiments show that methanol is employed as the hydrogen atom donor. Recycle tests and gram-scale reaction elucidate the practicability of the heterogeneous ceramic BCN photoredox system. It provides an alternative to homogeneous catalysts in the valuable carbon radical intermediates formation. Moreover, the metal-free system is also applicable to late-stage functionalization of anti-inflammatory drugs, such as naproxen and ibuprofen, which enrich the chemical toolbox.

Nickel-Catalyzed C(sp3)-H Arylation of Diarylmethane Derivatives with Aryl Fluorides

Li, Jie,Wu, Chen,Zhou, Bihui,Walsh, Patrick J.

, p. 2993 - 2999 (2018/03/09)

A novel nickel-catalyzed C(sp3)-H arylation with nonactivated aryl fluorides is reported. The use of 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes) as a ligand was found to be critical to the success of the reaction. This new method enables the synthesis of a wide range of triarylmethane derivatives.

LDA-Mediated Synthesis of Triarylmethanes by Arylation of Diarylmethanes with Fluoroarenes at Room Temperature

Ji, Xinfei,Huang, Tao,Wu, Wei,Liang, Fang,Cao, Song

supporting information, p. 5096 - 5099 (2015/11/03)

A practical and convenient approach for the secondary C(sp3)-H arylation of diarylmethanes with various fluoroarenes is described. The reaction proceeds smoothly in the presence of LDA (lithium diisopropylamide) at room temperature and affords triarylmethanes in moderate to high yields.

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