42104-70-1Relevant articles and documents
METHOD OF PRODUCING ACRYLOYL MONOMERS AND ACRYLOYL-BASED POLYMERS
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Paragraph 0068, (2022/01/04)
Embodiments of the present disclosure are directed to a method of making a reaction inhibiting polymer having a formula of M-CO-NR. The method may comprise reacting PAA with an organic coupling reagent and at least one alicyclic amine to produce the reaction inhibiting polymer. In accordance with another embodiment of the present disclosure, a method of making an acryloyl monomer having a formula of R?a#191-CO-NR may comprise reacting an acrylic acid with an organic coupling reagent and an alicyclic amine to form the acryloyl monomer. R?a#191 may be an alkylene moiety, M may be a poly(acrylic) acid backbone. NR may be an alicyclic amine moiety coupled to the polymer backbone or coupled to the alkylene moiety.
Radical α,β-Dehydrogenation of Saturated Amides via α-Oxidation with TEMPO under Transition Metal-Free Conditions
Wang, Mei-Mei,Sui, Guo-Hui,Cui, Xian-Chao,Wang, Hui,Qu, Jian-Ping,Kang, Yan-Biao
, p. 8267 - 8274 (2019/06/27)
A transition metal-free radical process for the selective α,β-dehydrogenation of saturated amides under mild conditions is developed. Utilizing radical activation strategy, the challenging issue associated with the low α-acidity of amides is resolved. For the first time, α,β-unsaturated Weinreb amides and acrylamides could be efficiently prepared directly from corresponding saturated amides. Mechanistic studies confirm the radical nature of this transformation. Two gram scale α,β-dehydrogenation have also been performed to demonstrate the utility of this method.
COMPOSITIONS AND METHODS FOR MODULATING PPP2R1A
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Paragraph 0599; 0600; 0607; 0634, (2018/08/26)
Disclosed herein, inter alia, are compositions and methods useful for modulating PPP2R1 A and for the treatment of cancer.