5211-23-4

Basic information

• Product Name: N-CARBOBENZYLOXY-L-PROLINE METHYL ESTER
• Synonyms: N-CARBOBENZYLOXY-L-PROLINE METHYL ESTER;N-Z-L-proline methyl ester, 97%;N-Cbz proline methylester;(S)-1-Benzyl 2-Methyl pyrrolidine-1,2-dicarboxylate;N-Benzyloxycarbonyl-L-proline Methyl ester;N-Z-L-proline methyl ester 97%;S-1-CBZ-Pyrrolidine-2-carboxylic acid Methyl Ester CBZ-D-Proline Methyl Ester;Cbz-Pro-Ome
• CAS NO: 5211-23-4
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.29
• Product Categories: Amino Acid Derivatives;Peptide Synthesis;Proline
• Mol File: 5211-23-4.mol

Chemical Properties

• Boiling Point: 375°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.175 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.02E-06mmHg at 25°C
• Refractive Index: n20/D 1.5217(lit.)
• Storage Temp.: 2-8°C
• PKA: -3.40±0.40(Predicted)
• CAS DataBase Reference: N-CARBOBENZYLOXY-L-PROLINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-CARBOBENZYLOXY-L-PROLINE METHYL ESTER(5211-23-4)
• EPA Substance Registry System: N-CARBOBENZYLOXY-L-PROLINE METHYL ESTER(5211-23-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 5211-23-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
N-Carbobenzyloxy-L-proline methyl ester is used as a key intermediate for the synthesis of various organic molecules. Its unique structure and reactivity make it suitable for the formation of complex organic compounds through chemical reactions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, N-Carbobenzyloxy-L-proline methyl ester is used as a substrate for the synthesis of peptides and other bioactive molecules. Its ability to be easily modified and incorporated into larger molecular structures contributes to the development of new drugs and therapeutic agents.
Used in Peptide Chemistry:
N-Carbobenzyloxy-L-proline methyl ester is used as a versatile building block in peptide chemistry. Its ester form allows for the formation of peptide bonds and the creation of peptide-based compounds with potential applications in medicine and biotechnology.
Overall, N-Carbobenzyloxy-L-proline methyl ester plays a crucial role in organic synthesis and drug discovery by providing a versatile and adaptable platform for the creation of various bioactive molecules. Its applications in different industries highlight its importance in the development of new chemical compounds and therapeutic agents.

InChI:InChI=1/C14H17NO4/c1-18-13(16)12-8-5-9-15(12)14(17)19-10-11-6-3-2-4-7-11/h2-4,6-7,12H,5,8-10H2,1H3/t12-/m0/s1

Upstream product

• 67-56-1 methanol 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 110761-01-8 N-(tert-butyldimethylsilyloxycarbonyl)-L-proline methyl ester 
• 100-39-0 benzyl bromide 
• 501-53-1 benzyl chloroformate 
• 147-85-3 L-proline 
• 186581-53-3 diazomethane 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 4525-33-1 dimethyl dicarbonate 
• 5672-83-3 Z-L-GluOMe 

Downstream Products

• 214072-10-3 (5S)-2-Methoxy-1-[(benzyloxy)carbonyl]-5-methoxycarbonylpyrrolidine 
• 51207-68-2 (2S)-N-Benzyloxycarbony-2-(1'-hydroxy-1'-methylethyl)pyrrolidine 
• 113557-12-3 benzyl (S)-(-)-2-(hydroxy(diphenyl)methyl)-1-pyrrolidine carboxylate 
• 6216-63-3 N-Cbz-Prolinol 
• 71461-30-8 (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester 
• 75857-94-2 (5S)-N-(benzyloxycarbonyl)-5-methoxycarbonyl-2-pyrrolidinone 
• 93271-97-7 1-benzyl 2-methyl (2S)-5-hydroxypyrrolidine-1,2-dicarboxylate 
• 34381-71-0 (S)-2-hydroxymethyl-1-methylpyrrolidine 
• 195453-57-7 2-tert-Butoxycarbonylmethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 157662-40-3 (R)-N-(benzoyloxycarbonyl)-allylproline methyl ester 
• 110529-22-1 (S)-diphenyl(1-methylpyrrolidin-2-yl)methanol 
• 111491-98-6 (2S)-2-Acetyl-N-(benzyloxycarbonyl)pyrrolidine 
• 221072-61-3 (2S)-benzyl 2-(1-methoxy-1-propenyl)-1-pyrrolidinecarboxylate 
• 5493-38-9 N-benzoyl-L-proline methyl ester 

Relevant articles and documents

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