610-53-7

Basic information

• Product Name: 2,4-DINITROACETANILIDE
• Synonyms: 2,4-DINITROACETANILIDE;P-ACETODINITRAMINE;1-Acetamido-2,4-dinitrobenzene;Acetamide, N-(2,4-dinitrophenyl)-;Acetamide,N-(2,4-dinitrophenyl)-;Acetanilide, 2',4'-dinitro-;n-(2,4-dinitrophenyl)-acetamid;N-(2,4-Dinitrophenyl)acetamide
• CAS NO: 610-53-7
• Molecular Formula: C₈H₇N₃O₅
• Molecular Weight: 225.16
• EINECS: 210-227-9
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 610-53-7.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-DINITROACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DINITROACETANILIDE(610-53-7)
• EPA Substance Registry System: 2,4-DINITROACETANILIDE(610-53-7)

Safety Data

• Hazardous Substances Data: 610-53-7(Hazardous Substances Data)

Usage

Description

2,4-Dinitroacetanilide is a chemical compound that is frequently utilized in the realms of dyes, pharmaceuticals, and chemical research. It manifests as light yellow crystals and is recognized as a hazardous substance due to its potential health effects, which include skin and eye irritation, digestion problems, and respiratory issues if mishandled or ingested. Additionally, it poses a threat to aquatic life. Chemically, it remains stable under normal temperatures and pressures, but it can react violently with strong oxidizing agents, necessitating proper handling and storage.

Uses

Used in Dye Industry:
2,4-Dinitroacetanilide is used as an intermediate in the synthesis of various dyes, contributing to the development of a wide range of colorants for different applications.
Used in Pharmaceutical Industry:
2,4-Dinitroacetanilide is used as a building block in the production of certain pharmaceuticals, playing a crucial role in the synthesis of drugs that address various health conditions.
Used in Chemical Research:
2,4-Dinitroacetanilide is employed as a reagent in chemical research, facilitating the exploration of new chemical reactions and the development of novel compounds.

Upstream product

• 108-24-7 acetic anhydride 
• 97-02-9 2,4-Dinitroanilin 
• 128915-25-3 N-(2,4-Dinitro-phenyl)-N'-p-tolyl-acetamidine 
• 128915-27-5 N-(4-Chloro-phenyl)-N'-(2,4-dinitro-phenyl)-acetamidine 
• 128915-24-2 N-(2,4-Dinitro-phenyl)-N'-(4-methoxy-phenyl)-acetamidine 
• 64-19-7 acetic acid 
• 100-01-6 4-nitro-aniline 
• 103-84-4 Acetanilid 
• 75-36-5 acetyl chloride 
• 60-35-5 acetamide 
• 99-65-0 meta-dinitrobenzene 
• 7647-01-0 hydrogenchloride 
• 861295-75-2 acetic acid-(N-chloro-2,4-dinitro-anilide) 
• 7697-37-2 nitric acid 

Downstream Products

• 97-02-9 2,4-Dinitroanilin 
• 6232-92-4 6-nitro-1H-benzo[d]imidazol-2-amine 
• 99-56-9 4-Nitrophenylene-1,2-diamine 
• 1792-40-1 6-nitro-2-methyl-1H-benzimidazole 
• 405314-01-4 1-hydroxy-2-methyl-6-nitrobenzimidazole 
• 861295-75-2 acetic acid-(N-chloro-2,4-dinitro-anilide) 
• 6373-15-5 acetic acid-(2,4-diamino-anilide) 
• 53987-32-9 4-nitro-2-aminoacetanilide 
• 91358-36-0 tetrabutylammonium salt of 2,4-dinitroacetanilide 
• 3531-19-9 2-chloro-4,6-dinitroaniline 
• 1792-40-1 2-methyl-5-nitrobenzimidazole 

Relevant articles and documents

Transition-metal-free mono- or dinitration of protected anilines

An amide-assisted arene nitration is presented, and both mono- and dinitration of protected anilines could be effected by using NaNO2 and NaNO3 as the mono- and bisnitrating agents, respectively. This divergent synthesis is transition-metal- and acid-free, and features a broad substrate scope, low cost, and ortho–para selectivity.

Conformational analysis of N-aryl-N-(2-azulenyl)acetamides

Aromatic amides bearing 2-azulenyl group on the amide nitrogen were synthesized and their structures were investigated. The π-electron density of the N-aryl group was found to influence the cis-trans conformational preferences of these compounds in solution. X-ray crystallography revealed that the plane of the 2-azulenyl ring has a strong tendency to lie coplanar with the amide plane when the azulene group is located on the same side as the amide oxygen atom.

SO42-/SnO2: Efficient, chemoselective, and reusable catalyst for acylation of alcohols, phenols, and amines at room temperature

SO42-/SnO2 was employed for the acylation of a variety of alcohols, phenols, and amines under solvent-free conditions at room temperature. This method showed preferential selectivity for acetylation of the amino group in the presence of a hydroxyl group. The reported method is simple, mild, and environmentally viable, using several other acid anhydrides at room temperature. Copyright Taylor & Francis Group, LLC.