72778-09-7

Basic information

• Product Name: N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester
• Synonyms: N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester
• CAS NO: 72778-09-7
• Molecular Weight: 765.711
• Mol File: 72778-09-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester(72778-09-7)
• EPA Substance Registry System: N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester(72778-09-7)

Safety Data

• Hazardous Substances Data: 72778-09-7(Hazardous Substances Data)

Upstream product

• 65750-59-6 2-(4-nitrobenzyloxycarbonylamino)ethanethiol 
• 78072-36-3 (5R,6S)-3-(Diphenoxy-phosphoryloxy)-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 72789-82-3 (3S,4R)-4-(2,2-dimethoxyethyl)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-2-oxoazetidine 
• 105995-50-4 magnesium 4-nitrobenzyl malonate 
• 64066-71-3 (3S,4R)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-4-(2-oxoethyl)-2-oxoazetidine 
• 76335-76-7 (+/-)-4β-carboxymethyl-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 133380-98-0 (5RS,6RS,8RS)-p-nitrobenzyl 3-diphenylthiophosphinoyl-6-(1-p-nitrobenzyloxycarbonyloxyethyl)-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 76335-78-9 p-nitrobenzyl (+/-)-cis-6β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-3,7-dioxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 106673-95-4 (6RS,9RS)-7-chloro-7-(1-hydroxyethyl)-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 76347-45-0 (+/-)-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-(3-p-nitrobenzyloxycarbonyl-2-oxopropyl)azetidin-2-one 
• 76335-78-9 (+/-)-p-nitrobenzyl 6α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-3,7-dioxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 76347-45-0 (+/-)-3β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4β-(3-p-nitrobenzyloxycarbonyl-2-oxopropyl)azetidin-2-one 
• 77447-98-4 (+/-)-4β-(2,2-dimethoxyethyl)-3β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 

Relevant articles and documents

Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics

Compounds of formula (I): STR1 (wherein R1 represents hydrogen or a hydroxy-protecting group, R2 and R3 represent hydrogen, alkyl or aryl; R4 represents optionally substituted alkyl, alicyclic heterocyclic, aryl

AN EFFICIENT CARBAPENEM SYNTHESIS VIA AN INTRAMOLECULAR WITTIG REACTION OF NEW TRIALKOXYPHOSPHORANE-THIOLESTERS

New trialkoxyphosphorane-thiolesters 10, obtained by reaction of oxalimides 9 with trialkyl phosphite, were efficiently cyclized by an intramolecular Wittig reaction to give carbapenems 11.

Studies on the Syntheses of Heterocyclic Compounds. Part 877. An Alternative Synthesis of Protected (+/-)-Thienamycin and a Related Compound

An alternative total synthesis of protected (+/-)-thienamycin (2) and an analogue is described. (+/-)-4β-(2,2-Dimethoxyethyl)-3α-*)-1-(-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one (5), prepared from isoxazoline derivatives (4), was conve