7379-35-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloropyridinium chloride is used as a catalyst for the one-pot pyrrolation/cyclization of anthranilic acids, which is a crucial step in the synthesis of fluorazone derivatives. These derivatives are important compounds in the pharmaceutical industry, as they possess potential applications in the development of new drugs and therapeutic agents.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-Chloropyridinium chloride is utilized as a catalyst to facilitate the formation of fluorazone derivatives from anthranilic acids. This application is significant because it allows for the efficient and selective synthesis of these valuable compounds, which can be further used in the development of various chemical products and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 7379-35-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,7 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7379-35:
(6*7)+(5*3)+(4*7)+(3*9)+(2*3)+(1*5)=123
123 % 10 = 3
So 7379-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H4ClN.ClH/c6-5-1-3-7-4-2-5;/h1-4H;1H
7379-35-3Relevant articles and documents
Efficient Phosphorus-Free Chlorination of Hydroxy Aza-Arenes and Their Application in One-Pot Pharmaceutical Synthesis
Wang, Jian,Li, Yan-Hui,Pan, Song-Cheng,Li, Ming-Fang,Du, Wenting,Yin, Hong,Li, Jing-Hua
supporting information, p. 146 - 153 (2020/03/10)
The chlorination of hydroxy aza-arenes with bis(trichloromethyl) carbonate (BTC) and SOCl2 has been effectively performed by refluxing with 5 wt % 4-dimethylaminopyridine (DMAP) as a catalyst. Various substrates are chlorinated with high yields. The obtained chlorinated aza-arenes can be used directly with simple workup for succedent one-pot synthesis on a large scale.
Use of the graebe-ullmann reaction in the synthesis of 8-methyl-γ- carboline and isomeric aromatic aza-γ-carbolines
Alekseev,Kurkin,Yurovskaya
, p. 1235 - 1250 (2013/03/13)
Two variants of the Graebe-Ullmann reaction were used to obtain 8-methyl-5H-pyrido[4,3-b]indole (8-methyl-γ-carboline) and the conditions for this reaction were optimized. The feasibility of using this method was studied for the synthesis of a series of isomeric aromatic aza-γ- carbolines from the corresponding 1-(pyridyl)-1H-1,2,3-triazolo[4,5-c]pyridines under thermal and microwave irradiation conditions.
