Welcome to LookChem.com Sign In|Join Free

Cas Database

80-48-8

80-48-8

Identification

  • Product Name:Methyl p-toluenesulfonate

  • CAS Number: 80-48-8

  • EINECS:201-283-5

  • Molecular Weight:186.232

  • Molecular Formula: C8H10O3S

  • HS Code:29051900

  • Mol File:80-48-8.mol

Synonyms:Methyl p-tosylate;Methyltoluene-4-sulfonate;Methyl tosylate;Methyl toluenesulfonate;Toluene-4-sulfonic acid methyl ester;p-Methylbenzenesulfonic acid methyl ester;NSC 406335;Methyl 4-methylbenzenesulfonate;p-Toluenesulfonicacid, methyl ester (6CI,7CI,8CI);Benzenesulfonic acid,4-methyl-, methyl ester;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Pictogram(s):CorrosiveC,HarmfulXn

  • Hazard Codes:C,Xn

  • Signal Word:Danger

  • Hazard Statement:H302 Harmful if swallowedH314 Causes severe skin burns and eye damage H317 May cause an allergic skin reaction

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. FIRST AID TREATMENT: CONTACT...WITH SKIN OR EYES IS INDICATION FOR RAPID AND PROLONGED IRRIGATION OF AREA WITH LARGE VOL OF WATER.

  • Fire-fighting measures: Suitable extinguishing media WATER OR FOAM MAY CAUSE FROTHING. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. ...DECONTAMINATION OF FLOORS & EQUIPMENT MAY BE EFFECTED BY FLUSHING WITH DILUTE ALKALI OR AMMONIA.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Usbiological
  • Product Description:Methyl p-Toluenesulfonate
  • Packaging:5g
  • Price:$ 312
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:Methyl p-Toluenesulfonate
  • Packaging:5g
  • Price:$ 55
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:Methyl p-Toluenesulfonate >98.0%(GC)
  • Packaging:25g
  • Price:$ 19
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:Methyl p-Toluenesulfonate >98.0%(GC)
  • Packaging:500g
  • Price:$ 71
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Methyl toluene-4-sulfonate 98%
  • Packaging:100 g
  • Price:$ 77
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Methyl-4-toluenesulfonate for synthesis. CAS 80-48-8, EC Number 201-283-5, chemical formula 4-(CH )C H SO CH ., for synthesis
  • Packaging:8083332500
  • Price:$ 375
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Methyl-4-toluenesulfonate for synthesis
  • Packaging:2.5 kg
  • Price:$ 358.9
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Methyl p-toluenesulfonate purum, ≥97.0% (GC)
  • Packaging:1l
  • Price:$ 231
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Methyl-4-toluenesulfonate for synthesis. CAS 80-48-8, EC Number 201-283-5, chemical formula 4-(CH )C H SO CH ., for synthesis
  • Packaging:8083339025
  • Price:$ 999
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Methyl-4-toluenesulfonate for synthesis
  • Packaging:25 kg
  • Price:$ 952.75
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 68 Articles be found

Ring contraction of N-acetyl-2-aryl-1,2,3,4-tetrahydro-4-quinolones with [hydroxy(tosyloxy)iodo]benzene to trans methyl N-acetyl-2-aryl-2,3-dihydroindol- 3-carboxylates

Kumar, Ashok,Kumar, Sunil,Gupta, Rakesh K.,Kumar, Devinder

, p. 680 - 682 (2007)

The ring contraction of N-acetyl-2-aryl-1,2,3,4-tetrahydro-4-quinolones with [hydroxy(tosyloxy)iodo]benzene to trans methyl N-acetyl-2-aryl-2,3- dihydroindol-3-carboxylates in trimethylorthoformate in good yield is described.

Iron(III)-Mediated Oxysulfonylation of Enamides with Sodium and Lithium Sulfinates

Halaczkiewicz, Miro,Kelm, Harald,Kramer, Philipp,Manolikakes, Georg,Sun, Yu

, (2020)

An iron-mediated vicinal difunctionalization of enamides and enecarbamates with sulfinic acid salts and alcohols is described. This reaction proceeds under mild conditions and furnishes the oxysulfonylated products in moderate to excellent yields. Moreover, the direct incorporation of sulfur dioxide into the sulfonylated products via organolithium chemistry has been achieved. The formed N-O-acetals are competent acylimine precursors. Their utilization as building blocks for the synthesis of biologically relevant β-amidosulfones is described as well.

Grob-type fragmentation of 5-oxabicyclo[2.1.1]hexane system: A strategy for synthesis of annulated and 2,2,5-trisubstituted tetrahydrofurans

Mahadevegowda, Surendra H.,Khan, Faiz Ahmed

, p. 8494 - 8504 (2013)

Acid mediated, efficient Grob-type fragmentation reaction facilitated by vicinal ketal and ester moieties in variety of 5-oxabicyclo[2.1.1]hexanes leading to the corresponding annulated and 2,2,5-trisubstituted tetrahydrofurans is reported. Among the Br?nsted and Lewis acids tested, BF 3·OEt2 appears to give the best results, furnishing near quantitative yield (>99%) of tetrahydrofuran tricarboxylate derivatives under mild reaction condition. In case of unsymmetrical monosubstituted 5-oxabicyclo[2.1.1]hexanes two regioisomeric products are obtained. A strategy to transform one of the ester groups of the title compounds to protected hydroxymethyl moiety was evolved, which allows access to differentially protected 2-hydroxymethyl THF derivatives upon fragmentation. Employing TiCl4/R or S-BINOL as chiral Lewis acid, an enantioselective fragmentation (up to 66% ee) was described for the meso bis-furan derivative.

Method for the Preparation of Diamine Derivative

-

Paragraph 0284-0288, (2021/03/23)

The present invention relates to high yield. The present invention relates to a process for preparing high purity ethaboxate p - toluenesulphonate or hydrates thereof. To the present invention, generation of a dielectric toxic substance and a side reaction product can be suppressed, and high yield, high purity of edoxaba p - toluenesulphonate or a hydrate thereof can be advantageously used.

A simple method for the synthesis of sulfonic esters

Bhatthula, Bharath Kumar Goud,Kanchani, Janardhan Reddy,Arava, Veera Reddy,Marata Chenna Subbarao, Subha

supporting information, p. 1 - 16 (2020/07/27)

An efficient and simple approach for the direct synthesis of aryl and heteroaryl sulfonic esters was developed using DMS and DES as alkoxysulfonylation reagents. The reaction is operationally simple and scalable. This protocol does not require solvent, expensive catalysts, base, ligand additives or other reagents. A wide range of sulfonic esters were synthesized in moderate to good chemical yields. This method has the advantage of low cost, facile and tolerated a wide range of substrates.

A Scalable Metal-, Azide-, and Halogen-Free Method for the Preparation of Triazoles

Clark, Peter R.,Hayes, Jerome F.,Tomkinson, Nicholas C. O.,Williams, Glynn D.

, p. 6740 - 6744 (2020/03/23)

A scalable metal-, azide-, and halogen-free method for the synthesis of substituted 1,2,3-triazoles has been developed. The reaction proceeds through a 3-component coupling of α-ketoacetals, tosyl hydrazide, and a primary amine. The reaction shows outstanding functional-group tolerance with respect to both the α-ketoacetal and amine coupling partners, providing access to 4-, 1,4-, 1,5-, and 1,4,5-substituted triazoles in excellent yield. This robust method results in densely functionalised 1,2,3-triazoles that remain challenging to prepare by azide–alkyne cycloaddition (AAC, CuAAC, RuAAC) methods and can be scaled in either batch or flow reactors. Methods for the chemoselective reaction of either aliphatic amines or anilines are also described, revealing some of the potential of this novel and highly versatile transformation.

6MNEP: A molecular cation with large hyperpolarizability and promise for nonlinear optical applications

Bloxham, Joseph C.,Brock, Daniel J.,Jackson, Erika W.,Johnson, Jeremy A.,Kenney, Karissa C.,Michaelis, David J.,Smith, Stacey J.,Valdivia-Berroeta, Gabriel A.,Wayment, Adam X.

supporting information, p. 11079 - 11087 (2020/09/09)

Molecular organic crystals are strategically designed for nonlinear optical applications using push-pull chromophores as the core feature. In this approach, electron-donating and accepting groups are connected through a π-conjugated bridge to obtain planar molecules with high hyperpolarizability. However, the non-centrosymmetric packing that is required for nonlinear optical (NLO) applications is a critical challenge that must be addressed to design useful materials. In this article, we present the new organic cation 6MNEP that shows a large hyperpolarizability and can be crystallized in ideal non-centrosymmetric structures for NLO applications, when paired with T and 4NBS anions. The 6MNEP cation was obtained by extending the conjugation length of already existing chromophores. We compare the 6MNEP crystals with other crystals that also have cations with extended conjugation lengths, but result in centrosymmetric crystal structures. Using the effective hyperpolarizability, we found 6MNEP-T and 6MNEP-4NBS to have 1.6 to 2.5 times larger macroscopic nonlinearities than benchmark NLO organic crystals. Additionally, the significantly lower absorption wavelength compared with other state-of-the-art crystals make 6MNEP-T and 6MNEP-4NBS promising materials for NLO applications like intense terahertz generation.

Process route upstream and downstream products

Process route

(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

di(p-tolyl) disulfide
103-19-5

di(p-tolyl) disulfide

toluene-4-sulfonamide
70-55-3

toluene-4-sulfonamide

1-(2-Hydroxy-3-bornyl)-harnstoff-p-toluolsulfonat

1-(2-Hydroxy-3-bornyl)-harnstoff-p-toluolsulfonat

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
In methanol; for 48h; Product distribution; Mechanism; Irradiation; λ=254 nm;
37.6%
22.5%
6.6%
4.1%
(1,2-dibromo-2-nitroethyl)benzene
3425-99-8

(1,2-dibromo-2-nitroethyl)benzene

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

nitrostyrene
5153-67-3

nitrostyrene

p-tolylsulphenyl toluene-p-sulphonate

p-tolylsulphenyl toluene-p-sulphonate

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
at 20 ℃; Product distribution; effect of solvents (MeOH, DMF);
methanol
67-56-1

methanol

nitromethane anion
18137-96-7

nitromethane anion

p-toluenesulfonyl fluoride
455-16-3

p-toluenesulfonyl fluoride

sodium tosylate
657-84-1

sodium tosylate

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
at 20 ℃; for 20h;
54%
37%
ethyl ester of p-toluenesulfonic acid
80-40-0

ethyl ester of p-toluenesulfonic acid

dimethyl methane phosphonate
756-79-6

dimethyl methane phosphonate

O-ethyl O-methyl methylphosphonate
18755-36-7

O-ethyl O-methyl methylphosphonate

Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
at 130 - 140 ℃; for 3.5h;
benzoic toluene-p-sulphonic anhydride
13079-28-2

benzoic toluene-p-sulphonic anhydride

Dimethyl phosphite
868-85-9

Dimethyl phosphite

benzoic acid methyl ester
93-58-3,5705-52-2,80226-58-0

benzoic acid methyl ester

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
In benzene; for 20h; Heating;
56%
62%
dimethyl benzoylphosphonate
18106-71-3

dimethyl benzoylphosphonate

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

benzoic acid methyl ester
93-58-3,5705-52-2,80226-58-0

benzoic acid methyl ester

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
In benzene; for 24h; Product distribution; Mechanism; Heating; variation of time and concentrations; other dialkyl acylphosphonates;
73%
98%
In benzene; for 12h; Yield given; Heating;
methanol
67-56-1

methanol

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
With [bis(acetoxy)iodo]benzene; at 20 ℃; for 0.25h; Reagent/catalyst;
99%
With Iron(III) nitrate nonahydrate; at 20 ℃; for 2h;
62%
With sulfuric acid; tetrabutylammonium perchlorate; In acetonitrile; Ambient temperature; anodic oxidation: graphite anode, stainless steel cathode; 0.05 A/cm2, 4.7 V, 4 F/mol;
45%
di(p-tolyl) disulfide
103-19-5

di(p-tolyl) disulfide

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
With sodium hypochlorite pentahydrate; In methanol; at 20 ℃; for 3h; Solvent;
35%
2,2,2-trifluoroethyl methyl ether
460-43-5

2,2,2-trifluoroethyl methyl ether

toluene-p-sulfonyl bromide
1950-69-2

toluene-p-sulfonyl bromide

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
With potassium carbonate; at 40 ℃; for 6h; Temperature;
84%
methanol
67-56-1

methanol

para-thiocresol
106-45-6

para-thiocresol

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

Conditions
Conditions Yield
With oxygen; 9-(2-mesityl)-10-methylacridinium perchlorate; at 20 ℃; for 36h; Sealed tube; Schlenk technique; Irradiation; Green chemistry;
65%

Global suppliers and manufacturers

Global( 155) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Wuhan Shengmao Corp
  • Business Type:Trading Company
  • Contact Tel:86-27-82853423, 82819281
  • Emails:sales@shengmaochem.com
  • Main Products:85
  • Country:China (Mainland)
  • Simagchem Corporation
  • Business Type:Manufacturers
  • Contact Tel:+86-592-2680277
  • Emails:sale@simagchem.com
  • Main Products:110
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Trading Company
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
  • Kono Chem Co.,Ltd
  • Business Type:Other
  • Contact Tel:86-29-86107037-8015
  • Emails:info@konochemical.com
  • Main Products:82
  • Country:China (Mainland)
  • EAST CHEMSOURCES LIMITED
  • Business Type:Manufacturers
  • Contact Tel:86-532-81906761
  • Emails:josen@eastchem-cn.com
  • Main Products:97
  • Country:China (Mainland)
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
  • COLORCOM LTD.
  • Business Type:Manufacturers
  • Contact Tel:+86-571-89007001
  • Emails:medkem@medkem.cn
  • Main Products:1
  • Country:China (Mainland)
  • Shaanxi BLOOM TECH Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-29-86470566
  • Emails:sales@bloomtechz.com
  • Main Products:79
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 80-48-8
Post Buying Request Now
close
Remarks: The blank with*must be completed