964-42-1

Basic information

• Product Name: 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID
• Synonyms: 1,3-diphenyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE);2,5-di(phenyl)-3-pyrazolecarboxylic acid;2,5-di(phenyl)pyrazole-3-carboxylic acid
• CAS NO: 964-42-1
• Molecular Formula: C₁₆H₁₂N₂O₂
• Molecular Weight: 264.29
• Mol File: 964-42-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 496.2°Cat760mmHg
• Flash Point: 253.9°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 1.16E-10mmHg at 25°C
• CAS DataBase Reference: 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID(964-42-1)
• EPA Substance Registry System: 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID(964-42-1)

Safety Data

• Hazardous Substances Data: 964-42-1(Hazardous Substances Data)

Usage

General Description

2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID is a chemical compound with the molecular formula C17H12N2O2. It is a member of the pyrazole carboxylic acid family and is commonly used in the field of medicinal chemistry for the synthesis of pharmaceutical compounds. 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID has been studied for its potential biological activities and is known to exhibit anti-inflammatory and anti-tumor properties. Its structure and properties make it a versatile building block for the development of new drugs and can also be used as a reference standard in chemical research. Additionally, this compound has also been studied for its potential use in the development of materials and polymers due to its unique chemical structure.

InChI:InChI=1/C16H12N2O2/c19-16(20)15-11-14(12-7-3-1-4-8-12)17-18(15)13-9-5-2-6-10-13/h1-11H,(H,19,20)/p-1

Upstream product

• 55849-26-8 (α-nitrobenzylidene)phenylhydrazine 
• 24652-31-1 1,3-diphenyl-1H-pyrazole-5-carbonitrile 
• 94209-24-2 2,5-diphenyl-2H-pyrazole-3-carboxylic acid ethyl ester 
• 87995-91-3 trans-3-(1,3-Diphenyl-pyrazol-5-yl)acrylsaeure-methylester 
• 14428-98-9 N-benzyl-N-(1-phenylethylidene)amine 
• 98-86-2 acetophenone 
• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 100-63-0 phenylhydrazine 
• 931-55-5 phenyl-diazene 
• 88330-82-9 ethylbenzoylpyruvate sodium salt 
• 3426-35-5 4,5-dihydro-1,3-diphenyl-1H-pyrazole-5-carbonitrile 
• 15424-14-3 N-phenylbenzohydrazonoyl chloride 
• 922-67-8 propynoic acid methyl ester 
• 87995-90-2 1,3-diphenyl-5-[(E)-2-phenylethenyl]-1H-pyrazole 

Downstream Products

• 1243251-70-8 C₂₆H₂₈N₂O₂ 
• 4492-01-7 1,3-diphenyl-1H-pyrazole 

Relevant articles and documents

New synthetic access to 3-fluoroalkyl-5-pyrazolecarboxylates and carboxylic acids

A novel process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and carboxylic acids is hereby presented. Easily accesible α-fluorinated ketimines were condensed with oxalyl monochloride derivatives, and the obtained vinamides underwent acid-catalyzed cyclization with substituted hydrazines. This highly efficient protocol can also be used for non-fluorinated C-3 and C-5 substituents.

(13)C Chemical Shifts and (1)H - (13)C Coupling Constants of N-Phenyl-, N-p-Fluorophenyl- and N-o-Nitrophenylpyrazoles

The (13)C chemical shifts and some (1)H - (13)C coupling constants of twelve N-arylpyrazoles are reported.The assignments were made by using the effects of a fluorine substituent and two-dimensional techniques. Key words: (13)C chemical shifts, (1)H - (13

4,5-Dihydroisoxazoles. Part 5. Addition Reactions of Diazoalkanes. Nitrile Imines and Nitrile Oxides to 3-Aryl-4-methylene-5-morpholino-4,5-dihydroisoxazoles

Some 5-morpholino-3-aryl-4-methylene-4,5-dihydroisoxazoles were reacted with nitrile oxides, diazoalkanes and nitrile imines.The corresponding cycloaddition products, namely spiro and spirobi derivatives, were obtained