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Cefminox sodium
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Name

Cefminox sodium

 EINECS N/A
CAS No. 75498-96-3 Density N/A
PSA 281.59000 LogP -2.14560
Solubility N/A Melting Point N/A
Formula C16H20N7NaO7S3 Boiling Point N/A
Molecular Weight 541.565 Flash Point N/A
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 75498-96-3 ((6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt) Hazard Symbols N/A
Synonyms

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(2-amino-2-carboxyethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, [6R-[6a,7a,7(S*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7S)- (9CI);Cefminox sodium;Cefminox sodium salt;Meicelin;

Article Data 1

Cefminox sodium Synthetic route

52-89-1

l-cysteine hydrochloride

57617-09-1

7β-chloroacetamido-7α-methoxy-3-(1-methyl-1H-tetrazole-5-mercaptomethyl)-3-cephem-4-carboxylic acid

75498-96-3

(6R,7S)-7-[(S)-2-(2-amino-2-carboxyethylmercapto)acetamido]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; sodium thiosulfate In water at 50℃; Concentration; Temperature;97.9%

Cefminox sodium Chemical Properties

IUPAC Name: Sodium (6R,7S)-7-[[2-(2-amino-3-hydroxy-3-oxopropyl)sulfanylacetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Systematic of Cefminox sodium (CAS NO.75498-96-3): Antibiotic MT-141 ; Meicelin ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6-alpha,7-alpha))-
CAS NO: 75498-96-3
Classification Code: Drug / Therapeutic Agent ; Reproductive Effect
Molecular Formula of Cefminox sodium (CAS NO.75498-96-3): C16H20N7NaO7S3
Molecular Weight: 541.5575
Molecular Structure:

H bond acceptors: 14
H bond donors: 5
Freely Rotating Bonds: 12
Polar Surface Area of Cefminox sodium (CAS NO.75498-96-3): 236.19 Å2

Cefminox sodium Uses

 Cefminox sodium (CAS NO.75498-96-3) is used as cephalosporin antibiotic fungi.

Cefminox sodium Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 8200mg/kg (8200mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
mouse LD50 intravenous 5200mg/kg (5200mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 1030, 1987.
rat LD50 intramuscular 9600mg/kg (9600mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
rat LD50 intraperitoneal 8550mg/kg (8550mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
rat LD50 intravenous 5700mg/kg (5700mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
rat LD50 oral > 15gm/kg (15000mg/kg)   Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.
rat LD50 subcutaneous > 15gm/kg (15000mg/kg)   Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984.

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