Boord Olefin Synthesis

L. C. Swallen, C. E. Boord, J. Am. Chem. Soc. 52, 651 (1930); 53, 1505 (1931); 55, 3293 (1933); H. B. Dykstra et al., ibid. 52, 3396 (1930).

Regiospecific synthesis of olefins from aldehydes and Grignard reagents by zinc induced reductive elimination of halogen and alkoxy groups:



C. Niemann, C. D. Wagner, J. Org. Chem. 7, 227 (1942); P. Bandart, Bull. Soc. Chim. 11, 336 (1944); L. Crombie, Quart. Rev. (London) 6, 131 (1952); M. Schlosser, Houben-Weyl 5/1b, 213 (1972). Application to taxanes: J. S. Yadav et al. Tetrahedron Letters 35, 3617 (1994); P. H. Beusker et al., Eur. J. Org. Chem. 1998, 2483.