Einhorn-Brunner Reaction

A. Einhorn et al., Ann. 343, 229 (1905); K. Brunner, Ber. 47, 2671 (1914); Monatsh. 36, 509 (1915).

Formation of substituted 1,2,4-triazoles by acid-catalyzed condensation of hydrazines or semicarbazides with diacylamines:



M. R. Atkinson, J. B. Polya, J. Chem. Soc. 1952, 3418; 1954, 141, 3319; Theilheimer, Synthetic Methods 9, No. 449 (1955); K. T. Potts, Chem. Rev. 61, 103 (1961); K. Hu et al., J. Org. Chem. 63, 4786 (1998). Cf. Pellizzari Reaction.