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 Niementowski Quinoline Synthesis
  • Niementowski Quinoline Synthesis
  • Niementowski Synthesis

    S. v. Niementowski, Ber. 27, 1394 (1894); 28, 2809 (1895); 38, 2044 (1905); 40, 4285 (1907).

    Formation of γ-hydroxyquinoline derivatives from anthranilic acids and carbonyl compounds:



    R. H. Manske, Chem. Rev. 30, 127 (1942); T. A. Williamson, Heterocyclic Compounds 6, 331 (1957); W. L. F. Armarego, s (Interscience, New York, 1967) p 74; E. Cuny et al., Tetrahedron Letters 21, 3029 (1980). Synthetic applications: B. P. Suthar, Indian J. Chem. 21B, 588 (1982); R. J. Chong et al., Tetrahedron Letters 27, 5323 (1986); M. S. Khajavi et al., Iran. J. Chem. Chem. Eng. 17, 29 (1988). Review: T. Hisano, Org. Prep. Proced. Int. 5, 145-193 (1973). Cf. Friedlaender Synthesis; Pfitzinger Reaction.


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