Rubottom Oxidation

A. G. Brook, D. M. Macrae, J. Organometal. Chem. 77, C19 (1974); A. Hassner et al., J. Org. Chem. 40, 3427 (1975); G. M. Rubottom et al., Tetrahedron Letters 1974, 4319.

Oxidation of enolsilanes with m-chloroperbenzoic acid (m-CPBA) to afford α-hydroxy ketones:



Synthetic applications: R. Gleiter et al., J. Org. Chem. 57, 252 (1992); C. R. Johnson et al., J. Am. Chem. Soc. 114, 9414 (1992); M. T. Crimmins et al., ibid. 115, 3146 (1993).