(CAS NO.: ), with other name of Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(1-piperazinyl)-, could be produced through many synthetic methods.

Following is one of the synthesis routes:

O-(p-chlorophenoxy)aniline hydrochloride (I) could react with ethyl chlorocarbonate (A) in pyridine ether to produce ethyl O-(p-chlorophenoxy)phenylcarbanilate (II), which is condensed with N-carbetoxypiperazine (B) by means of Na₂O or NaOCH₃ in refluxing benzene to afford ethyl 4-[(O-(p-chlorophenoxy)phenyl)carbamoyl]-1-piperazine carboxylate (III). This product is finally decarboxylated and cyclized with P₂O₅ in refluxing POCl₃.