- Production Method of Tioconazole
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(CAS NO.: ), with its systematic name of , 1-(2-((2-chloro-3-thienyl)methoxy)-2-(ichlorophenyl)ethyl)-, could be produced through many synthetic methods.
Following is one of the synthesis routes: 1-(2,4-yl)-2-(1-imidazolyl)ethanol (I) is condensed with 2-chloro-3-chloromethylthiophene (II) in the presence of NaH in refluxing THF to produce Tioconazole.
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