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Cyproheptadine hydrochloride

  • Name Cyproheptadine hydrochloride
  • EINECS213-535-1
  • CAS No. 969-33-5
  • DensityN/A
  • PSA3.24000
  • LogP5.43780
  • SolubilityN/A
  • Melting Point254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
  • FormulaC21H21N.HCl
  • Boiling Point440.1 °C at 760 mmHg
  • Molecular Weight323.865
  • Flash Point194.5 °C
  • Transport InformationUN 2811 6.1/PG 3
  • AppearanceN/A
  • Safety26-36
  • Risk Codes22-36/37/38
  • Molecular Structure
    Molecular Structure of 969-33-5 (CYPROHEPTADINE HYDROCHLORIDE)
  • Hazard SymbolsHarmfulXn
  • SynonymsHarmfulXn
  • Article Data2

Cyproheptadine hydrochloride Chemical Properties

Product Name: Cyproheptadine hydrochloride  
CAS: 969-33-5
Formula: C21H22ClN
Molecular Weight: 323.86
Molecular Structure of  Cyproheptadine hydrochloride (CAS NO.969-33-5):

Flash Point: 194.5 °C 
Enthalpy of Vaporization: 69.72 kJ/mol 
Boiling Point: 440.1 °C at 760 mmHg 
Vapour Pressure: 6.03E-08 mmHg at 25°C 
Product Categories: active pharmaceutical ingredients;serotonin receptor.

Cyproheptadine hydrochloride Toxicity Data With Reference

1.    

cyt-hmn:lyms 2200 µmol/L/24H-C

    ZEKIA5    Zeitschrift fuer Kinderheilkunde. 118 (1974),219.
2.    

orl-wmn TDLo:7 mg/kg/4W-C:GIT,LIV

    BMJOAE    British Medical Journal. 1 (1978),753.
3.    

orl-rat LD50:295 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),340.
4.    

ipr-rat LD50:52,400 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.
5.    

orl-mus LD50:69 mg/kg

    AGACBH    Agents and Actions, A Swiss Journal of Pharmacology. 4 (1974),264.
6.    

ipr-mus LD50:55,300 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.

Cyproheptadine hydrochloride Safety Profile

Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: jaundice, liver function tests impaired, gastrointestinal effects. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information about Cyproheptadine hydrochloride (CAS NO.969-33-5):
Hazard Codes: 
Xn:
Risk Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TM7050000
HazardClass: 6.1(b)
PackingGroup: III

Cyproheptadine hydrochloride Specification

  The chemical synonyms of Cyproheptadine hydrochloride (CAS NO.969-33-5) are 1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5-Dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5h-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl piperidinhydrochloride ; Cyproheptadienehydrochloride ; Nuran ; Periactinsyrup ; Periactinhydrochloride ; Periactinolhydrochloride  .

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