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Cyproheptadine hydrochloride

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Name

Cyproheptadine hydrochloride

EINECS 213-535-1
CAS No. 969-33-5 Density N/A
PSA 3.24000 LogP 5.43780
Solubility N/A Melting Point 254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Formula C21H21N.HCl Boiling Point 440.1 °C at 760 mmHg
Molecular Weight 323.865 Flash Point 194.5 °C
Transport Information UN 2811 6.1/PG 3 Appearance N/A
Safety 26-36 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 969-33-5 (CYPROHEPTADINE HYDROCHLORIDE) Hazard Symbols HarmfulXn
Synonyms

Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (8CI,9CI);Ciplactin;Nuran;Periactin;Periactin hydrochloride;Periactin syrup;Peritol;Practin;Triactin;VUFB 3511;

Article Data 2

Cyproheptadine hydrochloride Chemical Properties

Product Name: Cyproheptadine hydrochloride  
CAS: 969-33-5
Formula: C21H22ClN
Molecular Weight: 323.86
Molecular Structure of  Cyproheptadine hydrochloride (CAS NO.969-33-5):

Flash Point: 194.5 °C 
Enthalpy of Vaporization: 69.72 kJ/mol 
Boiling Point: 440.1 °C at 760 mmHg 
Vapour Pressure: 6.03E-08 mmHg at 25°C 
Product Categories: active pharmaceutical ingredients;serotonin receptor.

Cyproheptadine hydrochloride Toxicity Data With Reference

1.    

cyt-hmn:lyms 2200 µmol/L/24H-C

    ZEKIA5    Zeitschrift fuer Kinderheilkunde. 118 (1974),219.
2.    

orl-wmn TDLo:7 mg/kg/4W-C:GIT,LIV

    BMJOAE    British Medical Journal. 1 (1978),753.
3.    

orl-rat LD50:295 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),340.
4.    

ipr-rat LD50:52,400 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.
5.    

orl-mus LD50:69 mg/kg

    AGACBH    Agents and Actions, A Swiss Journal of Pharmacology. 4 (1974),264.
6.    

ipr-mus LD50:55,300 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.

Cyproheptadine hydrochloride Safety Profile

Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: jaundice, liver function tests impaired, gastrointestinal effects. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information about Cyproheptadine hydrochloride (CAS NO.969-33-5):
Hazard Codes: 
Xn:
Risk Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TM7050000
HazardClass: 6.1(b)
PackingGroup: III

Cyproheptadine hydrochloride Specification

  The chemical synonyms of Cyproheptadine hydrochloride (CAS NO.969-33-5) are 1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5-Dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5h-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl piperidinhydrochloride ; Cyproheptadienehydrochloride ; Nuran ; Periactinsyrup ; Periactinhydrochloride ; Periactinolhydrochloride  .

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