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Name	Epirubicin hydrochloride	EINECS	260-145-2
CAS No.	56390-09-1	Density	1.61 g/cm³
PSA	206.07000	LogP	1.50360
Solubility	N/A	Melting Point	185 °C dec
Formula	C₂₇H₂₉NO₁₁.HCl	Boiling Point	810.3 °C at 760 mmHg
Molecular Weight	579.99	Flash Point	443.8 °C
Transport Information	N/A	Appearance	Orange-red crystalline solid
Safety	36/37/38-45-46	Risk Codes	22-63-62-46-40
Molecular Structure		Hazard Symbols	Xn
Synonyms	5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,hydrochloride, (8S,10S)- (9CI);5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,hydrochloride, (8S-cis)-;4'-Epidoxorubicin hydrochloride;4'-epi-Adriamycinhydrochloride;Ellence;Epidoxorubicin hydrochloride;

Epirubicin hydrochloride Chemical Properties

IUPAC Name: (7S,9S)-7-[(2R,4S,5R,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione hydrochloride
Synonyms of Epirubicin hydrochloride (CAS NO.56390-09-1): (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside hydrochloride ; 4'-Epidoxorubicin hydrochloride ; 4'-Epi-Adriamycin hydrochloride ; Epidoxorubicin hydrochloride ; Farmorubicin ; Pharmorubicin
CAS NO: 56390-09-1
Molecular Formula: C₂₇H₂₉NO₁₁.HCl
Molecular Weight: 579.99
Molecular Structure:
EINECS: 260-145-2
Flash Point: 443.8 °C
Enthalpy of Vaporization: 123.51 kJ/mol
Boiling Point: 810.3 °C at 760 mmHg
Vapour Pressure: 9.64E-28 mmHg at 25°C
Melting Point: 185°C dec
Appearance: Orange-Red Crystalline Solid
Product Categories of Epirubicin hydrochloride (CAS NO.56390-09-1): Antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals

Epirubicin hydrochloride Uses

Epirubicin hydrochloride (CAS NO.56390-09-1) is used as an antineoplastic mainly used for treatment of acute and chronic leukemia, malignant lymphoma.

Epirubicin hydrochloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	2250ug/kg (2.25mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
mouse	LD50	intravenous	31500ug/kg (31.5mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
mouse	LD50	oral	> 2gm/kg (2000mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
mouse	LD50	subcutaneous	37500ug/kg (37.5mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
rat	LD50	intraperitoneal	10800ug/kg (10.8mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
rat	LD50	intravenous	17mg/kg (17mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
rat	LD50	oral	1350mg/kg (1350mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
rat	LD50	subcutaneous	17600ug/kg (17.6mg/kg)		Drugs in Japan Vol. -, Pg. 200, 1990.
women	TDLo	intravenous	1622mg/kg (1622mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Lancet. Vol. 2, Pg. 629, 1986.

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