- Ethanolamine
- ETHANOLAMINE PHOSPHATE
- Ethanolamine thioglycolate
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Cas Database |
| Name |
Ethanolamine |
EINECS | 205-483-3 |
| CAS No. | 141-43-5 | Density | 0.973 g/cm3 |
| PSA | 46.25000 | LogP | -0.36230 |
| Solubility | miscible with water | Melting Point |
10-11 °C(lit.) |
| Formula | C2H7NO | Boiling Point | 170.9 °C at 760 mmHg |
| Molecular Weight | 61.0837 | Flash Point | 93.3 °C |
| Transport Information | UN 2924 3/PG 3 | Appearance | clear liquid |
| Safety | 26-36/37/39-45 | Risk Codes | 20/21/22-34-39/23/24/25-23/24/25-10 |
| Molecular Structure |
|
Hazard Symbols |
 C, T
|
| Synonyms |
EPA Pesticide Chemical Code 011601;Ethanol, 2-amino;2-aminoethanol;Thiofaco M-50;Ethylolamine;colamine;beta-Aminoethyl alcohol;2-Ethanolamine;2-Aminoethyl alcohol;beta-Hydroxyethylamine;beta-Aminoethanol;1-Amino-2-hydroxyethane;Aminoethanol;Envision Conditioner PDD 9020;2-Hydroxyethylamine;Ethanol, 2-amino- (8CI,9CI);2-Hydroxyethanamine;Ethanol,2-amino-;Olamine;beta-Aminoethyl alcohol beta-Ethanolamine;2-Amino-1-ethanol;Chemical material series;MEA 141-43-5 Monoethanolamine;H-Gly-ol; |
Article Data | 257 |
Ethanolamine Synthetic route
- 141-43-5
ethanolamine
| Conditions | Yield |
|---|---|
| With sodium hydrogen sulfate; silica gel In methanol; dichloromethane at 20℃; for 3.5h; | 95% |
- 100-46-9
benzylamine
- 88891-55-8
5-(2-hydroxyethyl)hexahydro-1,3,5-dithiazine
A
- 2547-66-2
1,3,5-Tribenzyl-1,3,5-triazacyclohexane
B
- 141-43-5
ethanolamine
| Conditions | Yield |
|---|---|
| at 20℃; for 24h; | A 95% B n/a |
| Conditions | Yield |
|---|---|
| With hydrogen In para-xylene; isopropyl alcohol at 25℃; under 760.051 Torr; for 3h; | A 5% B 95% |
| Conditions | Yield |
|---|---|
| With sulfuric acid; hydrogen In water at 79.84℃; under 60006 Torr; | 92.3% |
| With zinc borohydride In tetrahydrofuran for 7h; Heating; | 70% |
| With sodium tetrahydroborate; iodine In tetrahydrofuran |
| Conditions | Yield |
|---|---|
| With caesium carbonate In methanol at 60℃; for 8h; | 92% |
- 24070-16-4
N-tritylethanolamine
- 141-43-5
ethanolamine
| Conditions | Yield |
|---|---|
| With sodium hydrogen sulfate; silica gel In methanol; dichloromethane at 20℃; for 3.5h; | 90% |
| Conditions | Yield |
|---|---|
| With ammonium formate; palladium on activated charcoal In methanol for 0.166667h; Heating; | 86% |
| With 9,10-Dicyanoanthracene In water; acetonitrile Irradiation; | 80% |
| With di-isopropyl azodicarboxylate In tetrahydrofuran at 20℃; for 336h; |
- 23147-58-2, 110822-84-9, 110822-85-0
glycolaldehyde dimer
- 141-43-5
ethanolamine
| Conditions | Yield |
|---|---|
| With ammonium hydroxide; Ni6AlO(z); hydrogen at 80℃; under 3750.38 Torr; for 3h; Autoclave; | 85% |
| With ammonia; hydrogen; cobalt/manganese/sodium/phosphorous reduced catalyst In water at 100℃; under 75007.5 Torr; for 8h; Product distribution / selectivity; Autoclave; |
- 26646-35-5
2-(3-nitrophenoxy)ethanamine
B
- 554-84-7
meta-nitrophenol
C
- 55131-09-4
N-(2-hydroxyethyl)-3-nitroaniline
D
- 141-43-5
ethanolamine
| Conditions | Yield |
|---|---|
| With deuteriated sodium hydroxide In water-d2 at 20℃; for 0.833333h; Smiles rearrangement; UV-irradiation; | A 15% B n/a C 73% D n/a |
| Conditions | Yield |
|---|---|
| With sodium tetrahydroborate In diethylene glycol dimethyl ether at 76 - 78℃; for 3h; | 70% |
| With lithium aluminium tetrahydride In tetrahydrofuran for 5h; |
Ethanolamine Chemical Properties
The molecular structure of Ethanolamine (CAS No. 141-43-5):
IUPAC Name: 2-Aminoethanol
Molecular Formula: C2H7NO
Molecular Weight: 61.10g/mol
EINECS: 205-483-3
Melting Point: 10.3 ºC
Freely Rotating Bonds: 3
Polar Surface Area: 46.25 Å2
Index of Refraction: 1.435
Molar Refractivity: 16.38 cm3
Molar Volume: 62.7 cm3
Polarizability: 6.49 ×10-24cm3
Surface Tension: 39.7 dyne/cm
Density: 0.973 g/cm3
Flash Point: 93.3 °C
Melting point: 10-11 °C(lit.)
Enthalpy of Vaporization: 47.43 kJ/mol
Boiling Point: 170.9 °C at 760 mmHg
Vapour Pressure: 0.458 mmHg at 25°C
EINECS: 205-483-3
Product Categories: Pharmaceutical Intermediates; Thanolamine Series; omega-Aminoalkanols; omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
Ethanolamine Production
Ethanolamine (CAS NO.141-43-5) is produced by reacting ethylene oxide with aqueous ammonia; the reaction also produces diethanolamine and triethanolamine.
Ethanolamine Toxicity Data With Reference
| 1. | ratLD50:1500mg/kg | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(9), Pg. 55, 1979. | ||
| 2. | ratLD50:1720mg/kg | Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977. | ||
| 3. | rabbitLD50:1mL/kg | Union Carbide Data Sheet. Vol. 1/13/1972, | ||
| 4. | mouseLD50:700mg/kg | Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 81, 1962. |
Ethanolamine Safety Profile
Hazard Codes: 
T 
C
Risk Statements: 20/21/22-34-39/23/24/25-23/24/25-10
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R34: Causes burns.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R10: Flammable.
Safety Statements: 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2924 3/PG 3
WGK Germany: 1
RTECS: KJ5775000
F: 8-10-23
HazardClass: 8
PackingGroup: III
Ethanolamine Specification
Ethanolamine , with CAS number of 141-43-5, can be called 1-Amino-2-hydroxyethane ; 2-Amino-1-ethanol ; 2-Aminoaethanol ; EPA Pesticide Chemical Code 011601 ; Glycinol (monoethanolamine) ; Monoaethanolamin ; Monoethanolamine . It can be used in organic synthesis.The extinguishing agent of Ethanolamine (CAS NO.141-43-5) are dry powder, foam, sand, carbon dioxide, water mist.
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