NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 207.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1974,p. 45.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans
NIOSH REL: (ETU) Use encapsulated form; minimize exposure

For occupational chemical analysis use NIOSH: Ethylene Thiourea, 5011.

The 2-Imidazolidinethione is an organic compound with the formula C₃H₆N₂S. The IUPAC name of this product is imidazolidine-2-thione . With the CAS registry number 96-45-7, it is also named as 1,3-Ethylene-2-thiourea ;  4,5-Dihydro-2-mercaptoimidazole ; Akrochem etu-22 ; Ethylene thiourea ; Mercaptoimidazoline ; Sodium-22 neoprene accelerator ; Tetrahydro-2H-imidazole-2-thione ; Urea, 1,3-ethylene-2-thio- ; Vulkacit NPV/C ; NA-22-D .

The 2-Imidazolidinethione is white to pale green crystalline powder which is slightly soluble in water. It is odorless when pure, but technical product may have an amine odor. This product is combustible. It is incompatible with acids and reducing agents. And it can react with acids to liberate hydrogen sulfide. In additoin, it may be sensitive to prolonged exposure to light.    

This product is used as rubber accelerator of neoprene rubber, chlorosulfonated polyethylene rubber, chlorine alcohol rubber and polyacrylate rubber. It is also used as brightener for copper plating and often used in conjunction with acid copper plating brightener M, SPS, etc. 2-Imidazolidinethione is harmful if swallowed. It may cause harm to the unborn child. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) Avoid exposure - obtain special instructions before use. 

The 2-Imidazolidinethione can be obtained by the following method. Adding 24 kg ethylenediamine , 48 kg industrial alcohol , 60 kg distilled water to reactor successively. Stirring, slowly adding 32 kg CS₂ and controlling the temperature at about 60 °C in the dropping process. Warming up to 100 °C after dropping, refluxing 1 h. Then adding 3.6 kg concentrated hydrochloric acid to reflux 9 ~ 10 h. Cooling crystallization. The product is washed with acetone . The yield is about 80% - 85%.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.66 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): -0.66 ; (4)ACD/LogD (pH 7.4): -0.66 ; (5)ACD/BCF (pH 5.5): 1 ; (6)ACD/BCF (pH 7.4): 1 ; (7)ACD/KOC (pH 5.5): 10.42 ; (8)ACD/KOC (pH 7.4): 10.42 ; (9)#H bond acceptors: 2 ; (10)#H bond donors: 2 ; (11)Index of Refraction: 1.625 ; (12)Molar Refractivity: 28.3 cm³ ; (13)Molar Volume: 79.9 cm³ ; (14)Polarizability: 11.21×10^-24 cm³ ; (15)Surface Tension: 61.1 dyne/cm ; (16)Enthalpy of Vaporization: 38.52 kJ/mol ; (17)Vapour Pressure: 4.26 mmHg at 25°C ; (18)Tautomer Count: 2 ; (19)Exact Mass: 102.025169 ; (20)MonoIsotopic Mass: 102.025169 ; (21)Topological Polar Surface Area: 56.2 ; (22)Heavy Atom Count: 6. People can use the following data to convert to the molecule structure. SMILES: S=C1NCCN1; InChI: InChI=1/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6).

The following is the toxicity data which has been tested.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	oral	3gm/kg (3000mg/kg)		Teratology, The International Journal of Abnormal Development. Vol. 21, Pg. 71, 1980.
mouse	LD50	unreported	7800mg/kg (7800mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 59, 1986.
rat	LD50	oral	1832mg/kg (1832mg/kg)		Bulletin of Environmental Contamination and Toxicology. Vol. 7, Pg. 19, 1972.