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ChemComm
Page 4 of 4
DOI: 10.1039/C5CC05926G
COMMUNICATION
Conclusions
Journal Name
Soc., 2012, 134, 9585; (h) C.-H. Wei, S. Mannathan and C.-H.
Cheng, Angew. Chem., Int. Ed., 2012, 51, 10592; (i) M.
Presset, Y. Coquerel and J. Rodriguez, ChemCatChem, 2012
,
In
summary,
the
synthesis
of
highly
strained
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bicyclic[3.n.1]alkenes has been achieved by a metal-catalyzed
Conia-ene reaction of 2-acetylenic ketones. The utility of this
6-endo-dig-cyclization reaction allows the synthesis of a
variety of bicyclic [3.n.1] systems that are present in many
natural products. Application of this method, including an
asymmetric version, are currently underway in our laboratory
and will be reported in due course.
9
10 S. T. Staben, J. J. Kennedy-Smith and F. D. Toste, Angew.
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The Department of Science and Technology (DST), New Delhi,
India, is acknowledged for the award of a Start-up Research
Grant (young scientists) to RC. SK thanks the Council of
Scientific and Industrial Research (CSIR), New Delhi, and KKG
thanks DST, New Delhi, for a research fellowship. The authors
thank Dr. S. Chandrasekhar for valuable discussions.
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4 | J. Name., 2012, 00, 1-3
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